FAQ

Diethylnitrosamine

Known as: N-NITROSODIETHYLAMINE, N-ethyl-N-nitroso-ethanamine, N,N-diethylnitrosamine 
A synthetic light-sensitive, volatile, clear yellow oil that is soluble in water, lipids, and other organic solvents. It is used as gasoline and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
05010015019362016

Related topics

Related topics

12 relations

Broader (2)

Alkylating AgentsNitrosamines
In Bloodadministration & dosageagonistsantagonists & inhibitors
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Narrower (2)

N-ethyl-N-hydroxyethylnitrosamineN-nitrosodiethanolamine

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
Diethylnitrosamine
agonists
Alkylating Agents
Nitrosamines
chemical synthesis
standards characteristics

Papers overview

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Highly Cited
2007
Highly Cited
2007
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production.
Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men. Similar gender disparity is seen in mice… (More)
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2007
2007
Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
CYP2E1 metabolizes many low-molecular weight toxins and carcinogens. Some in vitro experiments suggest that CYP2E1 may be… (More)
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Highly Cited
2007
Highly Cited
2007
Silymarin modulates the oxidant-antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats.
Oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage in a variety of liver… (More)
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Highly Cited
2005
Highly Cited
2005
IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis
IkappaB kinase beta (IKKbeta), required for NF-kappaB activation, links chronic inflammation with carcinogenesis. We investigated… (More)
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Highly Cited
2005
Highly Cited
2005
Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver.
Nitrosamine compounds are known hepatic carcinogens. In the metabolism of nitrosamines, such as N-nitrosodiethylamine (NDEA… (More)
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Highly Cited
2004
Highly Cited
2004
In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes
Methods are needed to study single molecules to reveal variability, interactions and mechanisms that may go undetected at the… (More)
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Highly Cited
2004
Highly Cited
2004
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
Genetically modified mice have been extensively used for analyzing the molecular events that occur during tumor development. In… (More)
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Highly Cited
2000
Highly Cited
2000
Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis.
Curcumin has been widely used as a spice and coloring agent in foods. Recently, curcumin was found to possess chemopreventive… (More)
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Highly Cited
1992
Highly Cited
1992
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
An acetyltransferase-overexpressing strain of Salmonella typhimurium (NM2009) has been used to investigate roles of human liver… (More)
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1983
1983
Kinetics of diethylnitrosamine hepatocarcinogenesis in the infant mouse.
Kinetics of hepatocarcinogenesis was evaluated in 15-day-old male C57BL/6J X C3HeB/FeJ F1 mice using a nontoxic carcinogenic dose… (More)
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