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While diet-induced obesity has been exclusively attributed to increased caloric intake from fat, animals fed a high-fat diet (HFD… Expand The global prevalence of obesity is increasing across most ages in both sexes. This is contributing to the early emergence of… Expand BACKGROUND & AIMS
The composition of the gut microbiome is affected by host phenotype, genotype, immune function, and diet. Here… Expand OBJECTIVE—Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously… Expand The identification of new pharmacological approaches to effectively prevent, treat, and cure the metabolic syndrome is of crucial… Expand BACKGROUND
Trials comparing the effectiveness and safety of weight-loss diets are frequently limited by short follow-up times and… Expand Research Methods and Procedures: High‐fat (HF) diet feeding can induce obesity and metabolic disorders in rodents that resemble… Expand The C-C motif chemokine receptor-2 (CCR2) regulates monocyte and macrophage recruitment and is necessary for macrophage-dependent… Expand The objective of the present study was to develop a rat model that replicates the natural history and metabolic characteristics… Expand Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism in peripheral tissues… Expand