Dideoxy Chain Termination DNA Sequencing

Known as: Sanger Sequencing 
DNA sequencing in which chain termination is caused by incorporation of a dideoxynucleotide into a growing DNA strand.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
010020019852018

Papers overview

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2014
2014
BACKGROUND Genome editing techniques, including ZFN, TALEN, and CRISPR, have created a need to rapidly screen many F1 individuals… (More)
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2014
2014
Background:Invasive lobular breast cancer (ILC) and lobular carcinoma in situ (LCIS) are characterised by loss of E-cadherin… (More)
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2014
2014
BACKGROUND Primary immunodeficiencies (PIDs) are a diverse group of disorders caused by multiple genetic defects. Obtaining a… (More)
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Highly Cited
2013
Highly Cited
2013
Mutation detection through exome sequencing allows simultaneous analysis of all coding sequences of genes. However, it cannot yet… (More)
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Highly Cited
2013
Highly Cited
2013
The advent of massive parallel sequencing is rapidly changing the strategies employed for the genetic diagnosis and research of… (More)
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Highly Cited
2013
Highly Cited
2013
The approval of vemurafenib in the US 2011 and in Europe 2012 improved the therapy of not resectable or metastatic melanoma… (More)
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2013
2013
BRAF and KRAS mutations in ovarian serous borderline tumours (OSBTs) and ovarian low-grade serous carcinomas (LGSCs) have been… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in codons 12 and 13 of the KRAS oncogene are relatively common in colorectal and lung adenocarcinomas. Recent data… (More)
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2009
2009
We have made an evaluation of mutation detection techniques for their abilities to detect mosaic mutations. In this study, Sanger… (More)
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2009
2009
Reliable identification of cancer-related mutations in TP53 is often problematic, as these mutations can be randomly distributed… (More)
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