Dichlororibofuranosylbenzimidazole

Known as: Dichlorobenzimidazole Riboside, 5,6-Dichloro-1-beta-D-ribofuranosyl-1-H-benzimidazol, Riboside, Dichlorobenzimidazole 
An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
020406019532017

Papers overview

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Highly Cited
2010
Highly Cited
2010
The major histocompatibility complex (MHC) genes code for the proteins responsible for pathogen recognition. The MHC class II DRB… (More)
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Highly Cited
2009
Highly Cited
2009
Transcription and splicing must proceed over genomic distances of hundreds of kilobases in many human genes. However, the rates… (More)
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Highly Cited
2009
Highly Cited
2009
High-throughput sequencing technologies offer new perspectives for biomedical, agronomical and evolutionary research. Promising… (More)
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Highly Cited
2005
Highly Cited
2005
In vertebrates, the genes of the major histocompatibility complex (MHC) are among the most debated candidates accounting for co… (More)
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Highly Cited
2005
Highly Cited
2005
We investigated the importance of the major histocompatibility complex (MHC) constitution on the parasite burden of free-ranging… (More)
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Highly Cited
2005
Highly Cited
2005
Major histocompatibility complex (MHC) variability is believed to be maintained by pathogen-driven selection, mediated either… (More)
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Highly Cited
1999
Highly Cited
1999
DRB is a classic inhibitor of transcription elongation by RNA polymerase II (pol II). Since DRB generally affects class II genes… (More)
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Highly Cited
1998
Highly Cited
1998
Recently, a positive and a negative elongation factor, implicated in 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB… (More)
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Highly Cited
1995
Highly Cited
1995
Production of full-length runoff transcripts in vitro and functional mRNA in vivo is sensitive to the drug 5,6-dichloro-1-beta-D… (More)
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Highly Cited
1988
Highly Cited
1988
We have developed an experimental paradigm to study the mechanism by which nerve growth factor (NGF) allows the survival of… (More)
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