Dicentric chromosome

Known as: Dicentric, dic 
An abnormal chromosome with two centromeres as opposed to the normal one centromere.
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Gene amplification plays important roles in the progression of cancer and contributes to acquired drug resistance during… (More)
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Highly Cited
2006
Highly Cited
2006
Somatic chromosome spreads from maize (Zea mays L.) plants containing B-A translocation chromosomes undergoing the chromosome… (More)
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Review
2006
Review
2006
The cytokinesis-block micronucleus (CBMN) assay was originally developed as an ideal system for measuring micronuclei (MNi… (More)
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Highly Cited
2001
Highly Cited
2001
Although mechanisms for chromosomal instability in tumors have been described in animal and in vitro models, little is known… (More)
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Highly Cited
2000
Highly Cited
2000
It has long been known that rearrangements of chromosomes through breakage-fusion-bridge (BFB) cycles may cause variability of… (More)
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Highly Cited
1999
Highly Cited
1999
Although broken chromosomes can induce apoptosis, natural chromosome ends (telomeres) do not trigger this response. It is shown… (More)
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Highly Cited
1995
Highly Cited
1995
Robertsonian translocations are the most common structural dicentric rearrangements in humans. The stability of these dicentrics… (More)
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Highly Cited
1992
Highly Cited
1992
Loss of telomeric DNA during cell proliferation may play a role in ageing and cancer. Since telomeres permit complete replication… (More)
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Review
1991
Review
1991
The Holy Grail of gerontologists investigating cellular senescence is the mechanism responsible for the finite proliferative… (More)
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Highly Cited
1989
Highly Cited
1989
We have screened for the presence of two centromere autoantigens, CENP-B (80 kDa) and CENP-C (140 kDa) at the inactive centromere… (More)
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