Dextran Sulfate Sodium

Known as: Sulfate, Sodium Dextran, Dextran Sulfate, Sodium, Sodium Dextran Sulfate 
A long chain polymer of sulfated glucose with strong hydrophilic properties that binds to various membranes. Dextran sulfate has been shown to… (More)
National Institutes of Health

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Dextran Sulfate

Papers overview

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Highly Cited
2014
Highly Cited
2014
Dextran sulfate sodium (DSS)-induced colitis in mice.
Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis and Crohn's Disease, are complex and multifactorial… (More)
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Highly Cited
2010
Highly Cited
2010
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
BACKGROUND The proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18 are central players in the pathogenesis of… (More)
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Review
2007
Review
2007
Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions
AbstractIndividuals diagnosed with ulcerative colitis face a significantly increased risk of developing colorectal dysplasia and… (More)
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Highly Cited
2006
Highly Cited
2006
Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.
Inflammatory bowel diseases, chronic inflammatory disorders, have been strongly linked with an increased risk of the development… (More)
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Highly Cited
2005
Highly Cited
2005
Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation.
Exposure to dextran sulfate sodium (DSS) induces acute colitis, which is normally resolved after DSS removal. To study chronicity… (More)
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Highly Cited
2004
Highly Cited
2004
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.
We evaluated the effects of rat anti-mouse IL-17 neutralizing monoclonal antibody (mAb) on the development of dextran sulfate… (More)
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Highly Cited
1999
Highly Cited
1999
Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium.
In this study we examined changes in colonic mucosal permeability induced by dextran sulfate sodium (DSS) during the acute phase… (More)
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Highly Cited
1999
Highly Cited
1999
Dextran Sulfate Sodium (DSS) Colitis in Rats (Clinical, Structural, and Ultrastructural Aspects)
Aim of this study was to assess the structural,ultrastructural, immunohistochemical, and clinicalaspects in Sprague-Dawley rats… (More)
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Highly Cited
1998
Highly Cited
1998
Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.
Dextran sulfate sodium (DSS)-induced murine colitis represents an experimental model for human inflammatory bowel disease. The… (More)
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Highly Cited
1993
Highly Cited
1993
Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin
The use of oral and intravenous cyclosporin represents a significant advance in the therapy of refractory inflammatory bowel… (More)
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