Desoxycorticosterone acetate

Known as: Deoxycorticosterone-21-acetate, Deoxycorticosterone 21 acetate, Acetate, Desoxycortone 
The 21-acetate derivative of desoxycorticosterone.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
RATIONALE Superoxide (O2(-) ) has been implicated in the pathogenesis of many human diseases including hypertension; however… (More)
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Highly Cited
2007
Highly Cited
2007
Hypertension promotes atherosclerosis and is a major source of morbidity and mortality. We show that mice lacking T and B cells… (More)
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Highly Cited
2003
Highly Cited
2003
Two mechanisms are proposed to account for the inhibition of myosin phosphatase (MP) involved in Ca2+ sensitization of vascular… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiotensin II-induced hypertension is associated with NAD(P)H oxidase-dependent superoxide production in the vessel… (More)
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Highly Cited
2003
Highly Cited
2003
Tetrahydrobiopterin is a critical cofactor for the NO synthases, and in its absence these enzymes become "uncoupled," producing… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVES To investigate the basal and NADH-stimulated superoxide (.O2-) production and inactivation by Cu/Zn superoxide… (More)
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Highly Cited
2001
Highly Cited
2001
We previously reported increased aortic reactive oxygen species (ROS) production in mineralocorticoid (deoxycorticosterone… (More)
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Highly Cited
1992
Highly Cited
1992
Unlike the non-renin-dependent hypertension associated with infrarenal aorta banding, an abnormal accumulation of fibrillar… (More)
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Highly Cited
1986
Highly Cited
1986
We have used rat cortical collecting tubules perfused in vitro to study the effects of antidiuretic hormone (ADH) and… (More)
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Highly Cited
1982
Highly Cited
1982
The aetiology of essential hypertension, a disease prevalent in cultured societies, is unknown. However, much evidence suggests… (More)
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