Depressive Disorder, Treatment-Resistant

Known as: Therapy Resistant Depression, Treatment-Resistant Depressive Disorders, Disorder, Treatment-Resistant Depressive 
Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
0204019652018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
BACKGROUND Ketamine has a rapid antidepressant effect in treatment-resistant depression (TRD). The effects on cognitive function… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2013
Highly Cited
2013
BACKGROUND Only a third of patients with depression respond fully to antidepressant medication but little evidence exists… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2011
2011
Identifying new treatment approaches for treatment resistant depression (TRD) is an important topic for translational psychiatry… (More)
Is this relevant?
2009
2009
INTRODUCTION There is now evidence that major depression is accompanied by an induction of inflammatory and oxidative and… (More)
Is this relevant?
2007
2007
INTRODUCTION Previous studies of patients with unipolar depression have shown that early decreases of EEG cordance (a new… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
2005
2005
Previous studies in unipolar depression have shown that early decreases in prefrontal values of the QEEG cordance measure… (More)
Is this relevant?
2005
2005
BACKGROUND Treatment resistant depression is a common clinical problem. Studies have shown that a large number of patients with… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
There is now some evidence that major depression is accompanied by an immune response with an increased production of pro… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The aims of the present study were to examine i) serum zinc (Zn) and copper (Cu) in treatment resistant depression (TRD); ii) the… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Opiates were used to treat major depression until the mid-1950s. The advent of opioids with mixed agonist-antagonist or partial… (More)
Is this relevant?