Demecolcine

Known as: Methylcolchicine, (-)-Colchamine, Demecolcine [Chemical/Ingredient] 
A colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin… (More)
National Institutes of Health

Papers overview

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2009
2009
This study aimed to evaluate the effect of demecolcine, a microtubule-depolymerizing agent, on microtubule kinetics; to determine… (More)
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2007
2007
OBJECTIVE Establishment of tetraploid ES cells. MATERIALS AND METHODS Mouse H-1 (ES) cells were polyploidized by demecolcine… (More)
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2006
2006
The present study demonstrated that demecolcine treatment for at least 30 min produces a membrane protrusion in metaphase II… (More)
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2005
2005
Demecolcine-induced enucleation (IE) of mouse oocytes has been shown to improve development to term of cloned mice. In this study… (More)
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Highly Cited
2003
Highly Cited
2003
Parallel imaging methods become increasingly available on clinical MR scanners. To investigate the potential of sensitivity… (More)
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Highly Cited
2003
Highly Cited
2003
Podosomes are actin- and fimbrin-containing adhesions at the leading edge of macrophages. In cells transfected with beta-actin… (More)
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2003
2003
Brief treatment of metaphase II (MII) stage porcine oocytes with 0.4 microg/mL demecolcine in the presence of 0.05 M sucrose… (More)
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2003
2003
Studies were designed to further explore the use of pharmacological agents to produce developmentally competent enucleated mouse… (More)
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Highly Cited
2002
Highly Cited
2002
The present study demonstrated that brief treatment of in vitro-matured porcine oocytes with demecolcine results in a membrane… (More)
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Highly Cited
1986
Highly Cited
1986
The growth of axons in the developing nervous system depends on the elongation of the microtubules that form their principal… (More)
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