Deletion Mutagenesis

Mutagenesis where the mutation is caused by the loss of DNA sequences within a gene. This may occur spontaneously in vivo or be experimentally… (More)
National Institutes of Health

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Topic mentions per year

1983-2017
010203019832017

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2010
2010
Mutagenesis by the overlap extension PCR has become a standard method of creating mutations including substitutions, insertions… (More)
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2001
Highly Cited
2001
A new reverse genetics method has been developed to identify and isolate deletion mutants for targeted plant genes. Deletion… (More)
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2001
Highly Cited
2001
This paper reports the first method for the construction of unmarked gene deletion mutants in the genus Rhodococcus. Unmarked… (More)
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1996
Highly Cited
1996
Human complement factor H controls spontaneous activation of complement in plasma and appears to play a role in distinguishing… (More)
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1996
Highly Cited
1996
Paxillin is a 68-kD focal adhesion phosphoprotein that interacts with several proteins including members of the src family of… (More)
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1994
1994
Human tryptophan hydroxylase has been expressed as a soluble and active form in Escherichia coli by fusion with an affinity tag… (More)
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1987
1987
Studies on human cytomegalovirus (CMV) have been limited by a paucity of molecular genetic techniques available for manipulating… (More)
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1985
Highly Cited
1985
A mutation of a cloned gene that has been made by introducing a transposon or some other selectable genetic determinant can be… (More)
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1984
Highly Cited
1984
A model is presented for deletion mutations whose formation is mediated by palindromic and quasipalindromic DNA sequences. It… (More)
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