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Delavirdine Mesylate

Known as: Delavirdine Mesylate [Chemical/Ingredient], Mesylate, Delavirdine 
A mesylate salt form of delavirdine, a synthetic, non-nucleoside reverse transcriptase inhibitor. In combination with other anti-retroviral drugs… Expand
National Institutes of Health

Related topics

Related topics

17 relations
Acquired Immunodeficiency SyndromeAlprazolamAstemizoleCisapride
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Broader (3)

DelavirdineIndolesPiperazines

Narrower (2)

RescriptorU-90152

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Determination of the Composition of Delavirdine Mesylate Polymorph and Pseudopolymorph Mixtures Using 13C CP/MAS NMR
  • P. Gao
  • Pharmaceutical Research
  • 2004
    • Corpus ID: 6122113
AbstractPurpose. The application of solid-state nuclear magnetic resonance for the quantitation of relative amounts of… Expand
Review
2002
Review
2002
Rifampin and rifabutin drug interactions: an update.
Rifampin is a potent inducer of cytochrome P-450 oxidative enzymes. A few examples of well-documented clinically significant… Expand
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1999
1999
Efficacy and safety of delavirdine mesylate with zidovudine and didanosine compared with two-drug combinations of these agents in persons with HIV disease with CD4 counts of 100 to 500 cells/mm3…
To evaluate the antiretroviral activity of delavirdine mesylate, a non-nucleoside reverse transcriptase inhibitor of HIV-1, we… Expand
Highly Cited
1998
Highly Cited
1998
Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.
Administration of delavirdine, an HIV-1 reverse transcriptase inhibitor, to rats or monkeys resulted in apparent loss of hepatic… Expand
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1998
1998
Pharmacokinetic drug-drug interaction study of delavirdine and indinavir in healthy volunteers.
The potential pharmacokinetic drug-drug interaction between delavirdine, a nonnucleoside analogue reverse transcriptase inhibitor… Expand
Highly Cited
1997
Highly Cited
1997
Pharmacokinetic study of the interaction between rifampin and delavirdine mesylate
To study the effect of rifampin (INN, rifampicin), a potent inducer of cytochrome P450, on the steady‐state pharmacokinetics of… Expand
Highly Cited
1997
Highly Cited
1997
Steady‐state pharmacokinetics of delavirdine in HIV‐positive patients: Effect on erythromycin breath test
  • C. Cheng, D E Smith, +7 authors P. Stetson
  • Clinical pharmacology and therapeutics
  • 1997
    • Corpus ID: 34122850
The steady‐state kinetics of delavirdine and desisopropyldelavirdine were evaluated in human immunodeficiency virus‐positive… Expand
1997
1997
Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection.
Delavirdine is a nonnucleoside reverse transcriptase inhibitor with in vitro activity against human immunodeficiency virus type 1… Expand
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1997
1997
Pharmacokinetic study of the interaction between rifabutin and delavirdine mesylate in HIV-1 infected patients.
The oxidative metabolism of delavirdine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, is mediated in part by… Expand
Review
1996
Review
1996
Delavirdine mesylate, a potent non-nucleoside HIV-1 reverse transcriptase inhibitor.
  • W. Freimuth
  • Advances in experimental medicine and biology
  • 1996
    • Corpus ID: 44512677
In summary, DLV has been well-tolerated in > 1,000 HIV-1 infected patients. Skin rash is the most prevalent medical event… Expand
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