Dbf4-dependent protein kinase complex

Known as: DDK, Dbf4-dependent protein kinase complex location 
A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
05101519732018

Papers overview

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2013
2013
Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly… (More)
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Highly Cited
2011
Highly Cited
2011
Proper eukaryotic DNA replication requires temporal separation of helicase loading from helicase activation and replisome… (More)
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Highly Cited
2010
Highly Cited
2010
Eukaryotic DNA replication uses kinase regulatory pathways to facilitate coordination with other processes during cell division… (More)
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Highly Cited
2010
Highly Cited
2010
The initiation of eukaryotic DNA replication is regulated by three protein kinase classes: cyclin-dependent kinases (CDK), Dbf4… (More)
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2009
2009
The essential S-phase kinase Cdc7-Dbf4 acts at eukaryotic origins of replication to trigger a cascade of protein associations… (More)
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Highly Cited
2008
Highly Cited
2008
Meiosis differs from mitosis in that DNA replication is followed by the segregation of homologous chromosomes but not sister… (More)
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Highly Cited
2008
Highly Cited
2008
S-phase cyclin-dependent kinase Cdc28-Clb5 (CDK-S) and Dbf4-dependent kinase Cdc7-Dbf4 (DDK) are highly conserved kinases well… (More)
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Highly Cited
2006
Highly Cited
2006
Origins of DNA replication are licensed in G1 by recruiting the minichromosome maintenance (MCM) proteins to form a… (More)
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2000
2000
In all eukaryotes, the initiation of DNA synthesis requires the formation of prereplicative complexes (pre-RCs) on replication… (More)
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1980
1980
The speech intelligibility and articulatory impairment of 32 spastic and 18 athetoid males, aged 17-55, were examined. Selection… (More)
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