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DW-116

Known as: DW 116 
National Institutes of Health

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2 relations

Broader (2)

FluoroquinolonesPiperazines

Papers overview

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2005
2005
Developmental toxicity assessment of the new fluoroquinolone antibacterial DW‐116 in rabbits
DW‐116 is a newly developed fluoroquinolone antibacterial with a broad spectrum against both Gram‐positive and Gram‐negative… 
2004
2004
Peri- and postnatal developmental toxicity of the fluoroquinolone antibacterial DW-116 in rats.
2003
2003
Transplacental pharmacokinetics of the new fluoroquinolone DW-116 in pregnant rats.
2003
2003
Fetal and maternal tissue distribution of the new fluoroquinolone DW-116 in pregnant rats.
2000
2000
Embryo lethality and teratogenicity of a new fluoroquinolone antibacterial DW-116 in rats
Abstract DW-116, 1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-l-piperazinyl)-1, 4-dihydro-4-oxoquinolone-3-carboxylic acid… 
1998
1998
Safety, tolerability and pharmacokinetics of the new long-acting quinolone DW-116 after single and multiple dosing in healthy subjects.
The safety, tolerability and pharmacokinetics of DW-116, a new fluoroquinolone with a broad antibacterial spectrum, were… 
1998
1998
Resistance mechanism ofAcinetobacter spp. strains resistant to DW-116, a new quinolone
DW-116 is a new fluoroquinolone antimicrobial agent with a broad spectrum. In order to elucidate the resistance mechanism to DW… 
1997
1997
In-vitro and in-vivo activities of DW-116, a new fluoroquinolone.
DW-116 is a novel fluoroquinolone that was two- to four-fold more active than rufloxacin and less active than sparfloxacin… 
1997
1997
Pharmacokinetics of 1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1- piperazinyl)-1,4-dihydro-4-oxoquinolone-3-carboxylic acid hydrochloride (DW-116), a new quinolone antibiotic in rats.
The objectives of this study were to characterize the pharmacokinetics of 1-5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1… 
1996
1996
원보 : 신규 퀴놀론 항균제 DW-116 의 소핵시험
DW-116 {1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrochloride} is… 
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