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DUSP4 gene

Known as: MKP2, MAP KINASE PHOSPHATASE 2, DUSP4 
This gene is involved in the dephosphorylation of MAPK1 and MAPK3.
National Institutes of Health

Papers overview

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2015
2015
Using DNA methylation and gene expression profiling of diffuse large B cell lymphoma (DLBCL) samples, Schmid et al. find that the… Expand
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Highly Cited
2013
Highly Cited
2013
Basal-like breast cancer (BLBC) is an aggressive disease that lacks a clinically approved targeted therapy. Traditional… Expand
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Highly Cited
2013
Highly Cited
2013
Gain-of-function mutations in KRAS and BRAF genes are found in up to 50% of colorectal cancers. These mutations result in the… Expand
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Highly Cited
2012
Highly Cited
2012
Neoadjuvant chemotherapy (NAC) induces a pathological complete response (pCR) in ∼30% of patients with breast cancer. However… Expand
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Highly Cited
2012
Highly Cited
2012
T cell-dependent B-cell responses decline with age, suggesting defective CD4 T-cell function. CD4 memory T cells from individuals… Expand
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Highly Cited
2010
Highly Cited
2010
Mutations of the KRAS oncogene are predictive for resistance to treatment with antibodies against the epithelial growth factor… Expand
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Highly Cited
2009
Highly Cited
2009
To address the biological heterogeneity of lung cancer, we studied 199 lung adenocarcinomas by integrating genome-wide data on… Expand
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2009
2009
Abstract Protein tyrosine kinases have important roles in spermatozoa; however, little is known about the presence and regulation… Expand
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Highly Cited
2006
Highly Cited
2006
Increased hepatic gluconeogenesis is an important contributor to the fasting hyperglycemia found in Type 2 diabetic patients. Low… Expand
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Highly Cited
1995
Highly Cited
1995
The mitogen-activated protein kinase (MAPK) also known as extracellular signal-regulated kinase (ERK) plays a crucial role in… Expand
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