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DUSP10 wt Allele

Known as: Dual Specificity Phosphatase 10 wt Allele, MKP-5, MKP5 
Human DUSP10 wild-type allele is located in the vicinity of 1q41 and is approximately 41 kb in length. This allele, which encodes dual specificity… Expand
National Institutes of Health

Related topics

Related topics

8 relations
1q41DUSP10 geneDUSP10 protein, humanDephosphorylation
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Papers overview

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2019
2019
Protective Function of Mitogen‐Activated Protein Kinase Phosphatase 5 in Aging‐ and Diet‐Induced Hepatic Steatosis and Steatohepatitis
Nonalcoholic fatty liver disease is currently the most common liver disease and is a leading cause of liver-related morbidity and… Expand
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2017
2017
Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways.
Previous reports showed that nepetoidin B (NTB), a natural product isolated from many herbs, has anti-fungal and anti-bacterial… Expand
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2015
2015
Regulation of Inflammatory Cytokine Production by MKP-5 in Macrophages.
Mitogen-activated protein kinases (MAPKs) include p38 MAPKs, c-Jun N-terminal kinases (JNKs) and Extracellular signal-regulated… Expand
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2015
2015
Mice lacking MKP-1 and MKP-5 Reveal Hierarchical Regulation of Regenerative Myogenesis.
The relative contribution of the MAP kinase phosphatases (MKPs) in the integration of MAP kinase-dependent signaling during… Expand
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2013
2013
Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5.
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in dystrophin. The degree of… Expand
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2012
2012
An essential function for MKP5 in the formation of oxidized low density lipid-induced foam cells.
The uptake of oxidized low density lipoprotein (ox-LDL) by macrophages usually leads to the formation of lipid-laden macrophages… Expand
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2008
2008
Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation.
Phosphorylation of the transcription factor interferon regulatory factor 3 (IRF3) is essential for the induction of promoters… Expand
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Highly Cited
2004
Highly Cited
2004
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5
Mitogen-activated protein (MAP) kinases are essential regulators in immune responses1, and their activities are modulated by… Expand
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2001
2001
A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.
Mitogen-activated protein kinases (MAPKs) are inactivated via dephosphorylation of either the threonine or tyrosine residue or… Expand
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Highly Cited
1999
Highly Cited
1999
MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases
Dual-specificity protein tyrosine phosphatases are a burgeoning family of enzymes, some of which, the MKPs, are implicated in the… Expand
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