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DT-5461a

National Institutes of Health

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DT 5461Polysaccharides

Papers overview

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1995
1995
DT-5461a, an antitumor synthetic lipid a analog, causes selective blood flow reduction in tumor tissue.
We previously reported that a synthetic low-toxicity lipid A analog, DT-5461a, exhibited a significant antitumor effect was… 
1994
1994
Antitumor synthetic lipid A analog DT-5461a upregulates cytokine expression in a murine macrophage cell line through LPS pathway.
We previously showed that DT-5461a, a lipid A analog, has antitumor activity and relatively low toxicity in animals. To clarify… 
1994
1994
Antitumor effect of DT-5461a, a synthetic low-toxicity lipid A analog, involves endogenous tumor necrosis factor induction subsequent to macrophage activation.
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