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DSB 120
Known as:
DSB-120
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Benzodiazepinones
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1996
1996
Preclinical pharmacology and antitumour activity of the novel sequence-selective DNA minor-groove cross-linking agent DSB-120
M. Walton
,
P. Goddard
,
L. Kelland
,
D. Thurston
,
K. Harrap
Cancer Chemotherapy and Pharmacology
1996
Corpus ID: 32706693
Abstract We examined the in vitro cytotoxicity, antitumour activity and preclinical pharmacokinetics of the novel sequence…
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Highly Cited
1994
Highly Cited
1994
Structure of a covalent DNA minor groove adduct with a pyrrolobenzodiazepine dimer: evidence for sequence-specific interstrand cross-linking.
Terence C. Jenkins
,
LAURENCE H. Hurley
,
Stephen Neidle
,
David E. Thurston
Journal of Medicinal Chemistry
1994
Corpus ID: 10846440
The structure of the interstrand cross-linked adduct formed between a C8-C8'-linked pyrrolobenzodiazepine (PBD) dimer (DSB-120; 1…
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1994
1994
DNA damage by anticancer agents and its repair: mapping in cells at the subgene level with quantitative polymerase chain reaction.
K. Grimaldi
,
J. Bingham
,
R. Souhami
,
J. Hartley
Analytical Biochemistry
1994
Corpus ID: 25715689
The quantitative polymerase chain reaction (QPCR)-based assay was used to measure DNA damage and repair to a small (523 bp…
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