FAQ

DRGX gene

Known as: paired-like homeodomain trancription factor DRG11, DRG11, PRRXL1, MOUSE, HOMOLOG OF 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
012319952016

Papers overview

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2010
2010
Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons.
Perception of noxious events relies on activation of complex central neuronal circuits. The spinal cord dorsal horn plays a… (More)
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2010
2010
The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway.
Little is known of transcriptional mechanisms underlying the development of the trigeminal (V) principal sensory nucleus (PrV… (More)
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2009
2009
Expression of a Prrxl1 alternative splice variant during the development of the mouse nociceptive system.
BACKGROUND Gene expression can be differentially regulated by alternatively spliced transcription factors, providing a mechanism… (More)
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2008
2008
In DRG11 knock-out mice, trigeminal cell death is extensive and does not account for failed brainstem patterning.
A previous study (Ding et al., 2003) showed that the homeodomain transcription factor DRG11 is necessary for pattern formation in… (More)
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2007
2007
DRG11 immunohistochemical expression during embryonic development in the mouse.
DRG11 is a paired domain transcription factor that is necessary for the assembly of the nociceptive circuitry in the spinal cord… (More)
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2007
2007
Development of the mesencephalic trigeminal nucleus requires a paired homeodomain transcription factor, Drg11.
The mesencephalic trigeminal nucleus (Me5) innervates muscle spindles and is responsible for receiving and transmitting… (More)
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2006
2006
Involvement of DRG11 in the development of the primary afferent nociceptive system.
During development, dorsal root ganglia (DRG) neurons differentiate in various subpopulations, nociceptive neurons belonging in… (More)
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2004
2004
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
DRG11, a transcription factor expressed in embryonic dorsal root ganglion (DRG) and dorsal horn neurons, has a role in the… (More)
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Highly Cited
2001
Highly Cited
2001
The Paired Homeodomain Protein DRG11 Is Required for the Projection of Cutaneous Sensory Afferent Fibers to the Dorsal Spinal Cord
Cutaneous sensory neurons that detect noxious stimuli project to the dorsal horn of the spinal cord, while those innervating… (More)
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1995
1995
Identification by differential RT-PCR of a novel paired homeodomain protein specifically expressed in sensory neurons and a subset of their CNS targets.
Sensory neurons are a major derivative of the neural crest for which there have been no definitive molecular markers in mammals… (More)
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