DRAP1 gene

Known as: DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) Gene, NC2-alpha, DR1 associated protein 1 
This gene plays a role in repression of transcription.
National Institutes of Health

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Homo sapiensTranscriptional RegulationTranscriptional Repressiondna binding

Papers overview

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2016
2016
Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease
Inferring molecular networks can reveal how genetic perturbations interact with environmental factors to cause common complex… (More)
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2004
2004
NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein.
Transcriptional activity of the TATA-binding protein (TBP) is controlled by a variety of proteins. The BTAF1 protein (formerly… (More)
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Review
2003
Review
2003
Nodal signaling in vertebrate development.
TGFss signals belonging to the Nodal family set up the embryonic axes, induce mesoderm and endoderm, pattern the nervous system… (More)
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2002
2002
Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1.
The formation and patterning of mesoderm during mammalian gastrulation require the activity of Nodal, a secreted mesoderm… (More)
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2002
2002
Functional dissection of a Rice Dr1/DrAp1 transcriptional repression complex.
We characterized rice cDNA sequences for OsDr1 and OsDrAp1, which encode structural homologs of the eukaryotic general repressors… (More)
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1998
1998
Histone Sequence Database: new histone fold family members
Searches of the major public protein databases with core and linker chicken and human histone sequences have resulted in the… (More)
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1997
1997
The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo.
A general repressor extensively studied in vitro is the human Dr1/DRAP1 heterodimeric complex. To elucidate the function of Dr1… (More)
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1997
1997
Saccharomyces cerevisiae BUR6 encodes a DRAP1/NC2alpha homolog that has both positive and negative roles in transcription in vivo.
BUR3 and BUR6 were identified previously by selecting for mutations that increase transcription from an upstream activating… (More)
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1997
1997
Functional dissection of a human Dr1-DRAP1 repressor complex.
The heterotetrameric Dr1-DRAP1 transcriptional repressor complex was functionally dissected. Dr1 was found to contain two domains… (More)
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Highly Cited
1996
Highly Cited
1996
Requirement of a corepressor for Dr1-mediated repression of transcription.
A Dr1-associated polypeptide (DRAP1) was isolated from HeLa cells and found to function as a corepressor of transcription… (More)
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