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DNM1L protein, human

Known as: DVLP protein, human, EC 3.6.5.5, dynamin 1-like protein, human 
Dynamin-1-like protein (736 aa, ~82 kDa) is encoded by the human DNM1L gene. This protein plays a role in mitochondrial and peroxisomal division.
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisDNM1L geneEndocytosisEnzyme Gene

Broader (3)

Guanosine Triphosphate PhosphohydrolasesMicrotubule-Associated ProteinsMitochondrial Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
Highly Cited
2014
Highly Cited
2014
SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome
Coronaviruses (CoV) have recently emerged as potentially serious pathogens that can cause significant human morbidity and death… 
Highly Cited
2013
Highly Cited
2013
Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen‐induced hepatocyte necrosis in mice
Acetaminophen (APAP) overdose is a major cause of hepatotoxicity and acute liver failure in the U.S., but the pathophysiology is… 
Highly Cited
2011
Highly Cited
2011
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
The purpose of our study was to better understand the relationship between mitochondrial structural proteins, particularly… 
Highly Cited
2009
Highly Cited
2009
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
The modification of proteins by the small ubiquitin‐like modifier (SUMO) is known to regulate an increasing array of cellular… 
Highly Cited
2003
Highly Cited
2003
Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA*
The structure of mitochondria is highly dynamic and depends on the balance of fusion and fission processes. Deletion of the… 
Highly Cited
2003
Highly Cited
2003
Dynamin-like Protein 1 Is Involved in Peroxisomal Fission*
The mammalian dynamin-like protein 1 (DLP1), a member of the dynamin family of large GTPases, possesses mechanochemical… 
Highly Cited
2003
Highly Cited
2003
Composition and dynamics of human mitochondrial nucleoids.
The organization of multiple mitochondrial DNA (mtDNA) molecules in discrete protein-DNA complexes called nucleoids is well… 
Highly Cited
2003
Highly Cited
2003
ARC5, a cytosolic dynamin-like protein from plants, is part of the chloroplast division machinery
Chloroplast division in plant cells is orchestrated by a complex macromolecular machine with components positioned on both the… 
Highly Cited
2001
Highly Cited
2001
Mammalian dynamin-like protein DLP1 tubulates membranes.
Dynamins are large GTPases with mechanochemical properties that are known to constrict and tubulate membranes. A recently… 
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