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DNAJA1 gene

Known as: NEDD7, DNAJA1, neural precursor cell expressed, developmentally down-regulated 7 
This gene plays a role in both folding and intracellular trafficking of proteins.
National Institutes of Health

Related topics

Related topics

5 relations
DNAJA1 protein, humancellular response to unfolded proteinintracellular protein transportprotein folding

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DNAJA1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
DnaJA1/Hsp40 Is Co-Opted by Influenza A Virus To Enhance Its Viral RNA Polymerase Activity
ABSTRACT The RNA-dependent RNA polymerase (RdRp) of influenza A virus is a heterotrimeric complex composed of the PB1, PB2, and… 
Highly Cited
2013
Highly Cited
2013
Hsp110 Is a Bona Fide Chaperone Using ATP to Unfold Stable Misfolded Polypeptides and Reciprocally Collaborate with Hsp70 to Solubilize Protein Aggregates*
Background: Hsp110s are considered as mere nucleotide exchange factors of the Hsp70s. Results: Human cytosolic Hsp110s can use… 
2012
2012
Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.
Highly Cited
2012
Highly Cited
2012
DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau.
Highly Cited
2010
Highly Cited
2010
Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer
RAS and RHO proteins, which contribute to tumorigenesis and metastasis, undergo posttranslational modification with an isoprenyl… 
Highly Cited
2008
Highly Cited
2008
Functional Divergence between Co-chaperones of Hsc70*
The ATPase cycle of the chaperone Hsc70 is regulated by co-chaperones; Hsp40/DnaJ-related proteins stimulate ATP hydrolysis by… 
Highly Cited
2007
Highly Cited
2007
New indicators of beef sensory quality revealed by expression of specific genes.
To identify new molecular markers of beef sensory quality, the transcriptomes of Longissimus thoracis muscle from 25 Charolais… 
Highly Cited
2006
Highly Cited
2006
Defining the Requirements for Hsp40 and Hsp70 in the Hsp90 Chaperone Pathway*
The Hsp90 chaperoning pathway and its model client substrate, the progesterone receptor (PR), have been used extensively to study… 
Highly Cited
2001
Highly Cited
2001
Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial.
R115777 is a nonpeptidomimetic enzyme-specific inhibitor of farnesyl protein transferase (FT) that was developed as a potential… 
Highly Cited
2000
Highly Cited
2000
Comparison of potential markers of farnesyltransferase inhibition.
Farnesyltransferase inhibitors (FTIs) were developed to target abnormal signaling pathways that are commonly activated in… 
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