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DNA topoisomerase II activity

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Lung Carcinoma Cell Line Cleavage Activity in an Adriamycin-resistant Human Small Cell Reduced DNA Topoisomerase II Activity and Drug-induced DNA
In a previous study we suggested that, in addition to the reduced Adriamycin accumulation, part of the resistance in an… 
1994
1994
EFFECT OF NB901 ON DNA TOPOISOMERASE II ACTIVITY AND C-HA-RAS GENE EXPRESSION IN HUMAN GASTRIC CANCER CELLS
DNA topoisomerase Ⅱ was isolated from gastric cancer BGC823 cellsand its activity was determined by using pBR322 DNA as the… 
1990
1990
Development and properties of an etoposide-resistant human leukaemic CCRF-CEM cell line.
Etoposide (VP-16) and several other unrelated anti-tumour agents appear to act by inhibiting the enzyme DNA topoisomerase II. We… 
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