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DNA-dependent Protein Kinase-targeting siDNA DT01

Known as: DNA-PK-targeting siDNA DT01, DT01 
A proprietary preparation of small interfering DNA (siDNA) molecules with potential chemo/radiosensitizing activity. By mimicking DNA double strand… 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
[Dbait: An innovative concept to inhibit DNA repair and treat cancer].
Review
2016
Review
2016
Dbait : un concept innovant pour inhiber la réparation de l’ADN et contribuer aux traitements des cancers
2015
2015
DNA repair inhibition by DT01 as an adjuvant therapy at each stage of hepatocellular cancer (HCC) treatment.
303 Background: Hepatocellular carcinoma (HCC) is the most common liver cancer. Radiofrequency ablation (RFA), transarterial… 
2015
2015
First-in-human phase I study of the DNA repair inhibitor DT01 in combination with radiotherapy in patients with in transit melanoma.
2555 Background: DT01 is a double stranded DNA oligonucleotide conjugated to cholesterol, which mimics "false" double strand… 
2015
2015
Concurrent Radiation Therapy and DNA Repair Inhibitor DT01 in Patients With in Transit Melanoma: Results of the First In-Human Phase 1 Study
2013
2013
Abstract 4483: Preclinical study of Dbait, an inhibitor of three DNA repair pathways, in breast cancer treatment.
Background: Five main types of therapies are available for the treatment of Breast Cancer (BC): surgery, radiation therapy… 
Review
2012
Review
2012
Measuring and modeling attentional dwell time
Attentional dwell time (AD) defines our inability to perceive spatially separate events when they occur in rapid succession. In… 
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