DNA demethylation

The removal of a methyl group from one or more nucleotides within an DNA molecule. [PMID:17208187]
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Global DNA demethylation in humans is a fundamental process that occurs in pre-implantation embryos and reversion to naive ground… (More)
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Highly Cited
2013
Highly Cited
2013
Dynamic changes in 5-methylcytosine (5mC) have been implicated in the regulation of gene expression critical for consolidation of… (More)
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2013
2013
Active DNA demethylation regulates epigenetic gene activation in numerous processes, but how the target site specificity of DNA… (More)
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Highly Cited
2011
Highly Cited
2011
Cytosine methylation is the major covalent modification of mammalian genomic DNA and plays important roles in transcriptional… (More)
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Highly Cited
2011
Highly Cited
2011
The discovery of cytosine hydroxymethylation (5hmC) suggested a simple means of demethylating DNA and activating genes. Further… (More)
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Highly Cited
2011
Highly Cited
2011
DNA methylation is a major epigenetic mechanism for gene silencing. Whereas methyltransferases mediate cytosine methylation, it… (More)
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Highly Cited
2009
Highly Cited
2009
www.sciencemag.org (this information is current as of August 17, 2009 ): The following resources related to this article are… (More)
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Highly Cited
2008
Highly Cited
2008
Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear. Using… (More)
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Review
2008
Review
2008
Patterns of DNA cytosine methylation are subject to mitotic inheritance in both plants and vertebrates. Plants use 5… (More)
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Highly Cited
2008
Highly Cited
2008
Although DNA methylation patterns in somatic cells are thought to be relatively stable, they undergo dramatic changes during… (More)
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