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DNA Topoisomerases, Type I

Known as: DNA Untwisting Protein, DNA Nicking-Closing Protein, DNA Untwisting Enzyme 
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and… 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Highly Cited
2011
Highly Cited
2011
DNA topoisomerases control DNA topology by breaking and rejoining DNA strands via covalent complexes with cleaved DNA substrate… 
Review
1998
Review
1998
  • C. Felix
  • Biochimica et biophysica acta
  • 1998
  • Corpus ID: 23938812
Highly Cited
1989
Highly Cited
1989
Yeast Saccharomyces cerevisiae strains that are permeable to the antitumor alkaloid camptothecin are killed by the drug if they… 
Highly Cited
1987
Highly Cited
1987
DNA topoisomerase I was purified to near homogeneity from a clonal line of human lymphoblastic leukemia cells, RPMI 8402, that is… 
Highly Cited
1985
Highly Cited
1985
Highly Cited
1983
Highly Cited
1983
Highly Cited
1983
Highly Cited
1983
The purified type II DNA topoisomerase from the embryos of Drosophila melanogaster exists in its native form as a dimer of 170… 
Highly Cited
1975
Highly Cited
1975
  • W. Keller
  • Proceedings of the National Academy of Sciences…
  • 1975
  • Corpus ID: 39037445
Closed-circular, superhelical DNA from simian virus 40 (SV40 DNA I) was treated with an excess of DNA-relaxing enzyme in the…