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DNA Restriction Enzymes

Known as: DNA Restriction Enzymes [Chemical/Ingredient], Restriction enzymes, DNA, Restriction Endonuclease 
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species… 
National Institutes of Health

Related topics

Related topics

29 relations
Enzyme GeneEsterase GeneHydrolaseHydrolysis
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Narrower (15)

McrBC endonucleaseMrr protein, E coliType I site-specific deoxyribonucleaseType II site-specific deoxyribonuclease
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Broader (1)

endodeoxyribonuclease

Papers overview

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Highly Cited
1996
Highly Cited
1996
Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.
A long-term goal in the field of restriction-modification enzymes has been to generate restriction endonucleases with novel… 
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Highly Cited
1990
Highly Cited
1990
Rapid and simple method for purification of nucleic acids
We have developed a simple, rapid, and reliable protocol for the small-scale purification of DNA and RNA from, e.g., human serum… 
Highly Cited
1989
Highly Cited
1989
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.
Gene splicing by overlap extension is a new approach for recombining DNA molecules at precise junctions irrespective of… 
Highly Cited
1985
Highly Cited
1985
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first… 
Review
1984
Review
1984
Ribosomal DNA spacer-length polymorphisms in barley: mendelian inheritance, chromosomal location, and population dynamics.
Spacer-length (sl) variation in ribosomal RNA gene clusters (rDNA) was surveyed in 502 individual barley plants, including… 
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Highly Cited
1983
Highly Cited
1983
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described. DNA… 
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Highly Cited
1981
Highly Cited
1981
DNA polymorphism detectable by restriction endonucleases.
Data on DNA polymorphisms detected by restriction endonucleases are rapidly accumulating. With the aim of analyzing these data… 
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Highly Cited
1980
Highly Cited
1980
Rapid isolation of high molecular weight plant DNA.
A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is… 
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Highly Cited
1979
Highly Cited
1979
Mathematical model for studying genetic variation in terms of restriction endonucleases.
  • M. Nei, W. Li
  • Proceedings of the National Academy of Sciences…
  • 1979
  • Corpus ID: 12939636
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this… 
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Highly Cited
1977
Highly Cited
1977
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
Circular (e.g. simian virus 40) and linear (e.g. λ phage) DNAs have been labeled to high specific radioactivities (>108 cts/min… 
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