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DNA Restriction Enzymes
Known as:
DNA Restriction Enzymes [Chemical/Ingredient]
, Restriction enzymes, DNA
, Restriction Endonuclease
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Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species…
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National Institutes of Health
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Related topics
Related topics
29 relations
Enzyme Gene
Esterase Gene
Hydrolase
Hydrolysis
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Narrower (15)
McrBC endonuclease
Mrr protein, E coli
Type I site-specific deoxyribonuclease
Type II site-specific deoxyribonuclease
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Broader (1)
endodeoxyribonuclease
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.
Y. G. Kim
,
J. Cha
,
S. Chandrasegaran
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 23988918
A long-term goal in the field of restriction-modification enzymes has been to generate restriction endonucleases with novel…
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Highly Cited
1992
Highly Cited
1992
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
E. Li
,
T. Bestor
,
R. Jaenisch
Cell
1992
Corpus ID: 19879601
Highly Cited
1990
Highly Cited
1990
Rapid and simple method for purification of nucleic acids
R. Boom
,
C. Sol
,
M. Salimans
,
C. Jansen
,
P. W. Wertheim-van Dillen
,
J. van der Noordaa
Journal of Clinical Microbiology
1990
Corpus ID: 25732153
We have developed a simple, rapid, and reliable protocol for the small-scale purification of DNA and RNA from, e.g., human serum…
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Highly Cited
1985
Highly Cited
1985
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
R. Saiki
,
S. Scharf
,
+4 authors
N. Arnheim
Science
1985
Corpus ID: 7251299
Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first…
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Review
1984
Review
1984
Ribosomal DNA spacer-length polymorphisms in barley: mendelian inheritance, chromosomal location, and population dynamics.
M. Saghai-Maroof
,
K. Solimán
,
R. Jorgensen
,
R. Allard
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 8198977
Spacer-length (sl) variation in ribosomal RNA gene clusters (rDNA) was surveyed in 502 individual barley plants, including…
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Highly Cited
1983
Highly Cited
1983
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
A. Feinberg
,
B. Vogelstein
Analytical Biochemistry
1983
Corpus ID: 2716180
Highly Cited
1981
Highly Cited
1981
DNA polymorphism detectable by restriction endonucleases.
M. Nei
,
F. Tajima
Genetics
1981
Corpus ID: 25436786
Data on DNA polymorphisms detected by restriction endonucleases are rapidly accumulating. With the aim of analyzing these data…
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Highly Cited
1980
Highly Cited
1980
Rapid isolation of high molecular weight plant DNA.
M. Murray
,
W. F. Thompson
Nucleic Acids Research
1980
Corpus ID: 16648561
A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is…
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Highly Cited
1979
Highly Cited
1979
Mathematical model for studying genetic variation in terms of restriction endonucleases.
M. Nei
,
W. Li
Proceedings of the National Academy of Sciences…
1979
Corpus ID: 12939636
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this…
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Highly Cited
1977
Highly Cited
1977
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
P. Rigby
,
M. Dieckmann
,
C. Rhodes
,
P. Berg
Journal of Molecular Biology
1977
Corpus ID: 9766073
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