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DNA Restriction Enzymes

Known as: DNA Restriction Enzymes [Chemical/Ingredient], Restriction enzymes, DNA, Restriction Endonuclease 
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species… Expand
National Institutes of Health

Related topics

Related topics

29 relations
Enzyme GeneEsterase GeneHydrolaseHydrolysis
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Narrower (15)

McrBC endonucleaseMrr protein, E coliType I site-specific deoxyribonucleaseType II site-specific deoxyribonuclease
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Broader (1)

endodeoxyribonuclease

Papers overview

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Highly Cited
1996
Highly Cited
1996
Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.
A long-term goal in the field of restriction-modification enzymes has been to generate restriction endonucleases with novel… Expand
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Highly Cited
1992
Highly Cited
1992
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
Gene targeting in embryonic stem (ES) cells has been used to mutate the murine DNA methyltransferase gene. ES cell lines… Expand
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Highly Cited
1990
Highly Cited
1990
Rapid and simple method for purification of nucleic acids.
We have developed a simple, rapid, and reliable protocol for the small-scale purification of DNA and RNA from, e.g., human serum… Expand
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Highly Cited
1989
Highly Cited
1989
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension.
Gene splicing by overlap extension is a new approach for recombining DNA molecules at precise junctions irrespective of… Expand
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Highly Cited
1989
Highly Cited
1989
Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.
We developed mobility shift analysis of single-stranded DNAs on neutral polyacrylamide gel electrophoresis to detect DNA… Expand
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Highly Cited
1985
Highly Cited
1985
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first… Expand
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Highly Cited
1983
Highly Cited
1983
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described. DNA… Expand
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Highly Cited
1981
Highly Cited
1981
DNA polymorphism detectable by restriction endonucleases.
Data on DNA polymorphisms detected by restriction endonucleases are rapidly accumulating. With the aim of analyzing these data… Expand
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Highly Cited
1980
Highly Cited
1980
Rapid isolation of high molecular weight plant DNA.
A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is… Expand
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Highly Cited
1979
Highly Cited
1979
Mathematical model for studying genetic variation in terms of restriction endonucleases.
  • M. Nei, W. Li
  • Proceedings of the National Academy of Sciences…
  • 1979
    • Corpus ID: 12939636
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this… Expand
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