DNA Replication Timing

Known as: Replication Timing Program, Replication Timing, DNA, Timing, DNA Replication 
The process that establishes the temporal order of the replication of segments of DNA along a chromosome or in an entire genome.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0246820012017

Papers overview

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2014
2014
Genomic DNA replicates in a choreographed temporal order that impacts the distribution of mutations along the genome. We show… (More)
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2012
2012
In higher eukaryotes, replication program specification in different cell types remains to be fully understood. We show for seven… (More)
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2011
2011
Previous experimental studies suggest that the mutation rate is nonuniform across the yeast genome. To characterize this… (More)
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2011
2011
Replication timing profiles are cell type–specific and reflect genome organization changes during differentiation. In this… (More)
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2011
2011
Genome-wide replication timing studies have suggested that mammalian chromosomes consist of megabase-scale domains of coordinated… (More)
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2011
2011
Many types of epigenetic profiling have been used to classify stem cells, stages of cellular differentiation, and cancer subtypes… (More)
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2010
2010
Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The INK4/ARF locus encodes three tumor suppressor genes (p15(Ink4b), Arf and p16(Ink4a)) and is frequently inactivated… (More)
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2003
2003
BACKGROUND The eukaryotic genome is divided into distinct replication timing domains, which are activated during S phase in a… (More)
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2002
2002
BACKGROUND Eukaryotic DNA replication starts at many origins. Some origins are used early in S phase, while others are programmed… (More)
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