DNA Repair Protein REV1

Known as: EC 2.7.7.-, Alpha-Integrin-Binding Protein 80, REV1 Homolog 
DNA repair protein REV1 (1251 aa, ~138 kDa) is encoded by the human REV1 gene. This protein plays a role in translesion DNA synthesis.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Appropriate repair of DNA lesions and the inhibition of DNA repair activities at telomeres are crucial to prevent genomic… (More)
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Highly Cited
2006
Highly Cited
2006
REV1 protein is a eukaryotic member of the Y family of DNA polymerases involved in the tolerance of DNA damage by replicative… (More)
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Highly Cited
2006
Highly Cited
2006
REV1 protein, a eukaryotic member of the Y family of DNA polymerases, is involved in the tolerance of DNA damage by translesion… (More)
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Highly Cited
2005
Highly Cited
2005
REV1 is central to the DNA damage response of eukaryotes through an as yet poorly understood role in translesion synthesis. REV1… (More)
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Highly Cited
2005
Highly Cited
2005
In response to DNA damage, the Rad6/Rad18 ubiquitin-conjugating complex monoubiquitinates the replication clamp proliferating… (More)
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Highly Cited
2005
Highly Cited
2005
The Rev1 DNA polymerase is highly specialized for the incorporation of C opposite template G. We present here the crystal… (More)
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Highly Cited
2005
Highly Cited
2005
The induction of potent CD8+ T cell responses by vaccines to fight microbes or tumors remains a major challenge, as many… (More)
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Highly Cited
2001
Highly Cited
2001
Abasic (AP) sites are one of the most frequently formed lesions in DNA, and they present a strong block to continued synthesis by… (More)
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Highly Cited
1997
Highly Cited
1997
Inherited mutations in BRCA1 predispose to breast and ovarian cancer, but the biological function of the BRCA1 protein has… (More)
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Highly Cited
1996
Highly Cited
1996
MUTAGENESIS induced by DNA damage in Saccharomyces cerevisiae requires the products of the REV1, REV3 and REV7 genes1. The Rev3… (More)
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