DNA-N1-methyladenine dioxygenase activity

Known as: AlkB 
Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and… (More)
National Institutes of Health

Papers overview

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2009
2009
For phytoremediation of organic contaminants, plants have to host an efficiently degrading microflora. To assess the role of… (More)
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2009
2009
Hydrocarbon seeps provide inputs of petroleum hydrocarbons to widespread areas of the Timor Sea. Alkanes constitute the largest… (More)
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2008
2008
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenine (epsilon A) originates from lipid peroxidation. Elevated… (More)
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Highly Cited
2006
Highly Cited
2006
An improved method was developed that allowed the specific detection of the gene alkB (coding for the rubredoxin dependent alkane… (More)
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Review
2003
Review
2003
All organisms have multiple DNA repair pathways to protect against alkylation-induced mutation and cell death. For nearly two… (More)
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Highly Cited
2002
Highly Cited
2002
Methylating agents generate cytotoxic and mutagenic DNA damage. Cells use 3-methyladenine-DNA glycosylases to excise some… (More)
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2000
2000
Fifty-four bacterial strains belonging to 37 species were tested for their ability to assimilate short chain and/or medium chain… (More)
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2000
2000
Escherichia coli alkB mutants are very sensitive to DNA methylating agents. Despite these mutants being the subject of many… (More)
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1996
1996
The Escherichia coli AlkB protein is involved in protecting cells against mutation and cell death induced specifically by SN2… (More)
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1983
1983
Seven mutants of Escherichia coli were isolated that are sensitive to methyl methane sulfonate but not to UV light. They… (More)
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