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DNA Hydroxymethylation

A DNA modification process where a hydrogen at the C5-position of a cytosine residue is replaced with a hydroxmethyl group.
National Institutes of Health

Papers overview

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2017
2017
INTRODUCTION DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer's disease (AD). The newly discovered 5… Expand
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2017
2017
DNA hydroxymethylation has recently been shown to play critical roles in regulating gene expression and terminal differentiation… Expand
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2017
2017
Epigenetic consequences of exposure to psychostimulants are substantial but the relationship of these changes to compulsive drug… Expand
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2016
2016
Methylated cytosines are associated with gene silencing. The ten-eleven translocation (TET) hydroxylases, which oxidize… Expand
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Highly Cited
2014
Highly Cited
2014
Background: The association between human blood DNA global methylation and global hydroxymethylation has not been evaluated in… Expand
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2014
2014
CCCTC-binding factor (CTCF) is a ubiquitously expressed multifunctional transcription factor characterized by chromatin binding… Expand
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2014
2014
BACKGROUND Hydroxymethylation of DNA at the C5 position of cytosine (5hmC) is recognized as an important epigenetic mark. The… Expand
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Highly Cited
2013
Highly Cited
2013
The genome-wide distribution patterns of the ‘6th base’ 5-hydroxymethylcytosine (5hmC) in many tissues and cells have recently… Expand
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Highly Cited
2012
Highly Cited
2012
Enhancers are developmentally controlled transcriptional regulatory regions whose activities are modulated through histone… Expand
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2012
2012
Artificial induction of active DNA demethylation appears to be a possible and useful strategy in molecular biology research and… Expand
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