DNA Hydroxymethylation

A DNA modification process where a hydrogen at the C5-position of a cytosine residue is replaced with a hydroxmethyl group.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
010203019762017

Papers overview

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2017
2017
Epidemiological studies have implicated fine particulate matter (PM2.5) as a risk factor for neurodegenerative diseases and… (More)
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2017
2017
INTRODUCTION DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer's disease (AD). The newly discovered 5… (More)
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2016
2016
DNA hydroxymethylation (5-hmC) is a kind of new epigenetic modification, which plays key roles in DNA demethylation, genomic… (More)
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Review
2016
Review
2016
The discovery of TET-mediated DNA hydroxymethylation as a mechanism of DNA demethylation, along with the observation of disrupted… (More)
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2016
2016
STUDY QUESTION In comparison to in vivo development, how do different conditions of in vitro culture ('one step' versus… (More)
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Highly Cited
2014
Highly Cited
2014
DNA methylation (5-methylcytosine [5mC]) is one of several epigenetic markers altered in Alzheimer's disease (AD) brain. More… (More)
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2014
2014
BACKGROUND Aging and chronic alcohol consumption are both modifiers of DNA methylation, but it is not yet known whether chronic… (More)
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2014
2014
BACKGROUND Hydroxymethylation of DNA at the C5 position of cytosine (5hmC) is recognized as an important epigenetic mark. The… (More)
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2014
2014
BACKGROUND Aging is one of the most important risk factors for cancer. It appears that aberrant epigenetic changes might be a… (More)
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2012
2012
Artificial induction of active DNA demethylation appears to be a possible and useful strategy in molecular biology research and… (More)
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