DNA Breaks

Known as: Break, DNA, Breaks, DNA, DNA Break 
Interruptions in the sugar-phosphate backbone of DNA.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2018
05101519812018

Papers overview

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Highly Cited
2015
Highly Cited
2015
Neuronal activity causes the rapid expression of immediate early genes that are crucial for experience-driven changes to synapses… (More)
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Highly Cited
2011
Highly Cited
2011
Classical non-homologous DNA end-joining (NHEJ) is a major mammalian DNA double-strand-break (DSB) repair pathway. Deficiencies… (More)
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Highly Cited
2010
Highly Cited
2010
Defective DNA repair by homologous recombination (HR) is thought to be a major contributor to tumorigenesis in individuals… (More)
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Highly Cited
2010
Highly Cited
2010
Repair of DNA double-strand breaks (DSBs) by homologous recombination is crucial for cell proliferation and tumour suppression… (More)
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Highly Cited
2009
Highly Cited
2009
Chromosomal translocations are a hallmark of leukemia/lymphoma and also appear in solid tumors, but the underlying mechanism… (More)
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2009
2009
BACKGROUND Etoposide is a cancer drug that induces strand breaks in cellular DNA by inhibiting topoisomerase II (topoII… (More)
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Highly Cited
2009
Highly Cited
2009
Meiotic crossover (CO) recombination facilitates evolution and accurate chromosome segregation. CO distribution is tightly… (More)
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2007
2007
Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes… (More)
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2004
2004
BACKGROUND Unrepaired DNA double-stranded breaks (DSBs) can result in the whole or partial loss of chromosomes. Previously, we… (More)
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Highly Cited
2002
Highly Cited
2002
Amplification of large genomic regions associated with complex translocations (complicons) is a basis for tumor progression and… (More)
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