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DNA-Binding Protein Ikaros

Known as: Lymphoid Transcription Factor LyF-1, ZNFN1A1, IKAROS Family Zinc Finger 1 Protein 1 
DNA-binding protein Ikaros (519 aa, ~58 kDa) is encoded by the human IKZF1 gene. This protein is a transcriptional enhancer that is involved in B… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid haematopoiesis that form an essential… Expand
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Highly Cited
2014
Highly Cited
2014
Drug With a (Re)Purpose Thalidomide, once infamous for its deleterious effects on fetal development, has re-emerged as a drug of… Expand
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Highly Cited
2014
Highly Cited
2014
In the 1950s, the drug thalidomide, administered as a sedative to pregnant women, led to the birth of thousands of children with… Expand
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Highly Cited
2011
Highly Cited
2011
The importance of individual microRNAs (miRNAs) has been established in specific cancers. However, a comprehensive analysis of… Expand
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Highly Cited
2010
Highly Cited
2010
Gene expression profiling of 207 uniformly treated children with high-risk B-progenitor acute lymphoblastic leukemia revealed 29… Expand
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Highly Cited
2010
Highly Cited
2010
To resolve the genetic heterogeneity within pediatric high-risk B-precursor acute lymphoblastic leukemia (ALL), a clinically… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Despite best current therapy, up to 20% of pediatric patients with acute lymphoblastic leukemia (ALL) have a relapse… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE The causes of the aggressive nature of BCR-ABL1-positive adult acute lymphoblastic leukemia (ALL) are unknown. To… Expand
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Highly Cited
2008
Highly Cited
2008
The Philadelphia chromosome, a chromosomal abnormality that encodes BCR–ABL1, is the defining lesion of chronic myelogenous… Expand
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Highly Cited
2007
Highly Cited
2007
Chromosomal aberrations are a hallmark of acute lymphoblastic leukaemia (ALL) but alone fail to induce leukaemia. To identify… Expand
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