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DLG4 gene

Known as: SAP-90, discs large homolog 4, PSD-95 
This gene is involved in synaptic plasticity and transmission.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Although synaptic loss is thought to be core to the pathophysiology of schizophrenia, the nature, consistency and magnitude of… Expand
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Highly Cited
2011
Highly Cited
2011
Homeostatic mechanisms are required to control formation and maintenance of synaptic connections to maintain the general level of… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic… Expand
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Highly Cited
2008
Highly Cited
2008
Postsynaptic density 95 (PSD-95) is an important regulator of synaptic structure and plasticity. However, its contribution to… Expand
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Review
2005
Review
2005
  • H. Cline
  • Current Biology
  • 2005
  • Corpus ID: 2319436
Recent studies have implicated a number of membrane-associated proteins, including the signaling pair neuroligin and beta… Expand
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Highly Cited
2002
Highly Cited
2002
At excitatory synapses, the postsynaptic scaffolding protein postsynaptic density 95 (PSD-95) couples NMDA receptors (NMDARs) to… Expand
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Highly Cited
2001
Highly Cited
2001
Increased glutamate-mediated excitotoxicity seems to play an important role in the pathogenesis of Huntington's disease (Tabrizi… Expand
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Highly Cited
2000
Highly Cited
2000
Mechanisms of ion channel clustering by cytoplasmic membrane-associated guanylate kinases such as postsynaptic density 95 (PSD-95… Expand
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Highly Cited
1995
Highly Cited
1995
Synapses are highly specialized sites of cell-cell contact involved in signal transfer. The molecular mechanisms modulating the… Expand
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Highly Cited
1993
Highly Cited
1993
A novel synapse-associated protein, SAP90, accumulates around the axon hillock of Purkinje cells in rat cerebellum. By immuno… Expand
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