DJ927

Known as: DJ 927, DJ-927 
A semi-synthetic orally-available taxane derivative with potent antineoplastic properties. DJ-927 binds to tubulin, promoting microtubule assembly… (More)

Topic mentions per year

Topic mentions per year

2003-2008
02420032008

Papers overview

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2008
2008
INTRODUCTION A phase I/II study was performed to assess the efficacy and toxicity of a new oral taxane in patients with recurrent… (More)
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2006
2006
3591 Background: DJ-927, a novel oral tubulin depolymerization inhibitor, causes apoptosis and DNA cell division arrest. It is… (More)
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2006
2006
4081 Background: Most 1st-line combination chemotherapy regimens in pts with advanced GC include 5-FU. Taxanes are also active… (More)
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2006
2006
17006 Background: For the treatment of NSCLC (1st and 2nd line) effective oral formulations of drugs are currently investigated… (More)
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2006
2006
2016 Background: DJ-927, an oral microtubule stabilizer, has impressive cytotoxic activity in taxane-resistant tumors and an… (More)
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Review
2006
Review
2006
The clinical and commercial success of the taxanes and vinca alkaloids resulted in a drive to improve on current formulations and… (More)
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2004
2004
2028 Background: DJ-927, a novel semi-synthetic taxane and a poor substrate of P-glycoprotein (Pgp), is orally bioavailable and… (More)
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2004
2004
DJ-927, currently undergoing Phase I clinical trial, is a new orally effective taxane with potent antitumor effects. The… (More)
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2003
2003
DJ-927 is a novel taxane, which was selected for high solubility, non-neurotoxicity, oral bioavailability, and potent antitumor… (More)
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