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DIS3 gene

Known as: DIS3, KIAA1008, RIBOSOMAL RNA-PROCESSING PROTEIN 44, S. CEREVISIAE, HOMOLOG OF 
This gene is involved in RNA processing.
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
PURPOSE At the molecular level, myeloma is characterized by copy number abnormalities and recurrent translocations into the… Expand
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Highly Cited
2014
Highly Cited
2014
We performed massively parallel sequencing of paired tumor/normal samples from 203 multiple myeloma (MM) patients and identified… Expand
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Highly Cited
2014
Highly Cited
2014
The eukaryotic RNA exosome processes and degrades RNA by directing substrates to the distributive or processive 3′ to 5… Expand
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Highly Cited
2012
Highly Cited
2012
Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal… Expand
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Highly Cited
2012
Highly Cited
2012
We have used whole exome sequencing to compare a group of presentation t(4;14) with t(11;14) cases of myeloma to define the… Expand
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2010
2010
The RNA processing exosome complex was originally defined as an evolutionarily conserved multisubunit complex of ribonucleases… Expand
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Highly Cited
2009
Highly Cited
2009
The exosome is a conserved macromolecular complex essential for RNA degradation. The nine-subunit core of the eukaryotic exosome… Expand
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Highly Cited
2007
Highly Cited
2007
The conserved core of the exosome, the major eukaryotic 3′ → 5′ exonuclease, contains nine subunits that form a ring similar to… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Cellular RNA metabolism has a broad range of functional aspects in cell growth and division, but its role in… Expand
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Highly Cited
1997
Highly Cited
1997
We identified a complex in S. cerevisiae, the "exosome," consisting of the five essential proteins Rrp4p, Rrp41p, Rrp42p, Rrp43p… Expand
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