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DIS3 gene
Known as:
DIS3
, KIAA1008
, RIBOSOMAL RNA-PROCESSING PROTEIN 44, S. CEREVISIAE, HOMOLOG OF
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This gene is involved in RNA processing.
National Institutes of Health
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Related topics
Related topics
4 relations
Narrower (1)
DIS3 wt Allele
Hydrolysis
RNA Degradation
RNA Processing
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Exonuclease domain mutants of yeast DIS3 display genome instability
Karissa L Milbury
,
B. Paul
,
A. Lari
,
C. Fowler
,
Ben Montpetit
,
Peter C. Stirling
The Nucleus
2019
Corpus ID: 67857079
ABSTRACT The exosome functions to regulate the cellular transcriptome through RNA biogenesis, surveillance, and decay. Mutations…
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2016
2016
Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression.
J. Hoskins
,
Abdisamad M. Ibrahim
,
+24 authors
L. Amundadottir
Human Molecular Genetics
2016
Corpus ID: 3501915
Genome-wide association studies (GWAS) have identified multiple common susceptibility loci for pancreatic cancer. Here we report…
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2016
2016
Collaborative Control of Cell Cycle Progression by the RNA Exonuclease Dis3 and Ras Is Conserved Across Species
Mark Snee
,
W. C. Wilson
,
+8 authors
J. Skeath
Genetics
2016
Corpus ID: 39223396
Dis3 encodes a conserved RNase that degrades or processes all RNA species via an N-terminal PilT N terminus (PIN) domain and C…
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2015
2015
An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster
A. B. Eberle
,
A. Jordán-Pla
,
+5 authors
N. Visa
PLoS Genetics
2015
Corpus ID: 16147217
RNA surveillance factors are involved in heterochromatin regulation in yeast and plants, but less is known about the possible…
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2014
2014
Looking into the barrel of the RNA exosome
C. Schneider
,
D. Tollervey
Nature Structural &Molecular Biology
2014
Corpus ID: 30160328
The exosome complex has key roles in RNA processing and quality control. Single-particle EM analyses now provide compelling…
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2014
2014
The RNA exosome affects iron response and sensitivity to oxidative stress
Borislava Tsanova
,
P. Spatrick
,
A. Jacobson
,
A. van Hoof
RNA: A publication of the RNA Society
2014
Corpus ID: 21110439
This paper describes the finding that inactivating the exosome in yeast leads to up-regulation of the iron uptake regulon. The up…
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2011
2011
Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant
Sarah B Smith
,
Daniel L. Kiss
,
Edward M. Turk
,
A. Tartakoff
,
Erik D. Andrulis
Yeast
2011
Corpus ID: 12853128
Subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular…
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Review
2010
Review
2010
Molecular mechanism of the Neurospora circadian oscillator
Jinhu Guo
,
Yi Liu
Protein & Cell
2010
Corpus ID: 195251727
Circadian clocks are the internal time-keeping mechanisms for organisms to synchronize their cellular and physiological processes…
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Highly Cited
2008
Highly Cited
2008
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p
K. Callahan
,
J. Butler
Nucleic Acids Research
2008
Corpus ID: 16667835
The RNA exosome processes and degrades RNAs in archaeal and eukaryotic cells. Exosomes from yeast and humans contain two active…
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2001
2001
The Saccharomyces cerevisiae small GTPase, Gsp1p/Ran, is involved in 3' processing of 7S-to-5.8S rRNA and in degradation of the excised 5'-A0 fragment of 35S pre-rRNA, both of which are carried out…
N. Suzuki
,
E. Noguchi
,
+5 authors
T. Nishimoto
Genetics
2001
Corpus ID: 33890020
Dis3p, a subunit of the exosome, interacts directly with Ran. To clarify the relationship between the exosome and the RanGTPase…
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