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DIS3 gene
Known as:
DIS3
, KIAA1008
, RIBOSOMAL RNA-PROCESSING PROTEIN 44, S. CEREVISIAE, HOMOLOG OF
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This gene is involved in RNA processing.
Topic mentions per year
Topic mentions per year
1992-2017
0
5
10
1992
2017
Related topics
Related topics
4 relations
Narrower (1)
DIS3 wt Allele
Hydrolysis
RNA Degradation
RNA Processing
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
DIS3 gene
Hydrolysis
RNA Processing
RNA Degradation
DIS3 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The molecular spectrum and clinical impact of DIS3 mutations in multiple myeloma.
Susann Weissbach
,
Christian Langer
,
+8 authors
Ellen Leich
British journal of haematology
2015
Multiple myeloma (MM) is a plasma cell neoplasm that presents with a major biological and clinical heterogeneity. We here…Â
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2015
2015
DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts.
Teresa Szczepinska
,
Katarzyna Kalisiak
,
+6 authors
Andrzej Dziembowski
Genome research
2015
Human DIS3, the nuclear catalytic subunit of the exosome complex, contains exonucleolytic and endonucleolytic active domains. To…Â
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Highly Cited
2014
Highly Cited
2014
Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.
Jens G. Lohr
,
Petar Stojanov
,
+18 authors
Todd R. Golub
Cancer cell
2014
We performed massively parallel sequencing of paired tumor/normal samples from 203 multiple myeloma (MM) patients and identified…Â
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2014
2014
Gene-dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression.
Florence L. M. de Groen
,
Oscar Krijgsman
,
+6 authors
B. Carvalho
Genes, chromosomes & cancer
2014
Colorectal cancer (CRC) development is in most cases marked by the accumulation of genomic alterations including gain of the…Â
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Highly Cited
2012
Highly Cited
2012
Clonal evolution in relapsed acute myeloid leukemia revealed by whole genome sequencing
Li Ding
,
Timothy J. Ley
,
+36 authors
John F. DiPersio
Nature
2012
Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal…Â
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Highly Cited
2012
Highly Cited
2012
Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.
Brian A Walker
,
Christopher P. Wardell
,
+10 authors
Gareth J Morgan
Blood
2012
We have used whole exome sequencing to compare a group of presentation t(4;14) with t(11;14) cases of myeloma to define the…Â
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2011
2011
Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.
Sarah Bartos Smith
,
Daniel Kiss
,
E. Abaci Turk
,
Alan Michael Tartakoff
,
Erik D. Andrulis
Yeast
2011
Subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular…Â
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2009
2009
The Exosome Regulates Circadian Gene Expression in a Posttranscriptional Negative Feedback Loop
Jinhu Guo
,
Ping Cheng
,
Haiyan Yuan
,
Yi Liu
Cell
2009
The eukaryotic circadian oscillators consist of autoregulatory negative feedback loops. However, little is known about the role…Â
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2001
2001
A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes
Ester Rozenblum
,
Pia Vahteristo
,
+21 authors
Olli-P. Kallioniemi
Human Genetics
2001
Chromosomal region 13q21-q22 harbors a putative breast cancer susceptibility gene and has been implicated as a common site for…Â
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1998
1998
Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3.
Takayuki Shiomi
,
K. Fukushima
,
N. Suzuki
,
Naoki Nakashima
,
Emiko Noguchi
,
Takaaki Nishimoto
Journal of biochemistry
1998
Saccharomyces cerevisiae Dis3p, which interacts with Ran/Gsp1p, complements Schizosaccharomyces pombe dis3-54. Consistent with…Â
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