DIHYDROPTERIDINE REDUCTASE

Known as: 6,7-Dihydropteridine Reductase, Reductase, 6,7-Dihydropteridine, Dihydropteridine Reductase [Chemical/Ingredient] 
An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
05101519692018

Papers overview

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2004
2004
To date there is ample evidence that patients with vitiligo accumulate millimolar concentrations of hydrogen peroxide (H2O2) in… (More)
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1992
1992
E. coli Dihydropteridine reductase, known to have a pterin-independent oxidoreductase activity with potassium ferricyanide as… (More)
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1987
1987
We gave folinic acid to three siblings, and to a fourth child, who have or had dihydropteridine reductase (DHPR) deficiency. The… (More)
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1987
1987
Aluminum intoxication due to aluminum-containing antacids or dialysate can cause encephalopathy in patients undergoing… (More)
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1987
1987
Deficiency of human dihydropteridine reductase (hDHPR) causes malignant hyperphenylalaninemia. We report the isolation of a cDNA… (More)
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Highly Cited
1982
Highly Cited
1982
Enzymatic diagnosis of hyperphenylalaninemia due to a deficiency of dihydropteridine reductase (DHPR) has previously been made by… (More)
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1980
1980
Three siblings with hyperphenylalaninemia were described, who showed convulsions and severe mental retardation despite dietary… (More)
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1978
1978
A severe deficiency of dihydropteridine reductase (DHPR) in liver, brain, and cultured skin fibroblasts was demonstrated in a… (More)
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Highly Cited
1975
Highly Cited
1975
The onset of neurologic symptoms in a child who had markedly elevated blood phenylalanine levels during the first two weeks of… (More)
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1972
1972
Dihydropteridine reductase has been obtained from sheep liver in essentially homogeneous form. The enzyme exists as a dimer of… (More)
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