DEBIO-025

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2014
02420062014

Papers overview

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2010
2010
Muscular dystrophy results in the progressive wasting and necrosis of skeletal muscle. Glucocorticoids such as prednisone have… (More)
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2010
2010
Cyclophilin A is a peptidyl-propyl isomerase that binds the capsid (p24) protein of HIV-1 and facilitates replication. We report… (More)
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2010
2010
A synthetic feline TRIM5-cyclophilin A fusion protein (feTRIMCyp) was generated and transduced into feline cells. feTRIMCyp was… (More)
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Highly Cited
2009
Highly Cited
2009
Viruses are obligate intracellular parasites and therefore their replication completely depends on host cell factors. In case of… (More)
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Highly Cited
2008
Highly Cited
2008
UNLABELLED Debio-025 is an oral cyclophilin (Cyp) inhibitor with potent anti-hepatitis C virus activity in vitro. Its effect on… (More)
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2008
2008
Debio-025 is a synthetic cyclosporine with no immunosuppressive capacity but a high inhibitory potency against cyclophilin A… (More)
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Highly Cited
2008
Highly Cited
2008
Muscular dystrophies comprise a diverse group of genetic disorders that lead to muscle wasting and, in many instances, premature… (More)
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Highly Cited
2007
Highly Cited
2007
Inhibition of mitochondrial permeability transition pore (mPTP) opening by cyclosporin A or ischemic postconditioning attenuates… (More)
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2007
2007
UNLABELLED Cyclosporin A (CsA) inhibits replication of the HCV subgenomic replicon, and this effect is believed to not be… (More)
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Highly Cited
2006
Highly Cited
2006
Cyclosporin A (CsA) inhibits the in vitro replication of HCV subgenomic replicons. We here report on the potent anti-HCV activity… (More)
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