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DDX6 gene

Known as: HLR2, RNA HELICASE, 54-KD, p54 
This gene plays a role in the translation of mRNA encoded by genes involved in cell proliferation and malignant transformation.
National Institutes of Health

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Related topics

8 relations
DDX6 protein, humanDNA RepairDNA ReplicationGenetic Translation Process
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DDX6 wt Allele

Papers overview

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2017
2017
DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes.
The innate immune system tightly regulates activation of interferon-stimulated genes (ISGs) to avoid inappropriate expression… Expand
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2016
2016
Transcriptome Analysis of Salt Stress Responsiveness in the Seedlings of Dongxiang Wild Rice (Oryza rufipogon Griff.)
Dongxiang wild rice (Oryza rufipogon Griff.) is the progenitor of cultivated rice (Oryza sativa L.), and is well known for its… Expand
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2015
2015
P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes
DDX6 is an abundant DEAD-box helicase associated with various complexes involved in mRNA decay and repression. Its interactome in… Expand
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2012
2012
miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies
This study shows that microRNA-503 interacts with the CUG-binding protein 1 (CUGBP1) mRNA and represses its translation by… Expand
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2011
2011
The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome
Viruses have to encapsidate their own genomes during the assembly process. For most RNA viruses, there are sequences within the… Expand
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Highly Cited
2009
Highly Cited
2009
microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells
Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3… Expand
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2007
2007
Xenopus Xp54 and human RCK/p54 helicases functionally replace yeast Dhh1p in brome mosaic virus RNA replication.
By using a Brome mosaic virus (BMV)-Saccharomyces cerevisiae system, we previously showed that the cellular Lsm1p-7p/Pat1p/Dhh1p… Expand
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Highly Cited
2006
Highly Cited
2006
Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54
RNA interference is triggered by double-stranded RNA that is processed into small interfering RNAs (siRNAs) by Dicer enzyme… Expand
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2005
2005
Structures of the MthK RCK domain and the effect of Ca2+ on gating ring stability.
MthK is a Ca2+-gated K+ channel from Methanobacterium autotrophicum. The crystal structure of the MthK channel in a Ca2+-bound… Expand
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Highly Cited
1989
Highly Cited
1989
Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.
Cloning and sequencing of cDNAs isolated from a rat cortex cDNA library reveals that a gene family encodes several highly… Expand
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