FAQ

DDX6 gene

Known as: HLR2, RNA HELICASE, 54-KD, p54 
This gene plays a role in the translation of mRNA encoded by genes involved in cell proliferation and malignant transformation.

Topic mentions per year

Topic mentions per year

1995-2018
02419952018

Related topics

Related topics

7 relations
DDX6 protein, humanDNA RepairDNA ReplicationGenetic Translation Process
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
DDX6 gene
Hydrolysis
DNA Repair
DNA Replication
Genetic Translation Process
RNA Processing

Papers overview

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2016
2016
DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex.
AF4/AFF1 and AF5/AFF4 are both backbones for the assembly of "super elongation complexes" (SECs) that exert 2 distinct functions… (More)
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2015
2015
The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs
In neural stem cells (NSCs), the balance between stem cell maintenance and neuronal differentiation depends on cell-fate… (More)
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2015
2015
Positive feedback of DDX6/c-Myc/PTB1 regulated by miR-124 contributes to maintenance of the Warburg effect in colon cancer cells.
The human DEAD/H-box RNA helicase gene DDX6 is a target of the t(11;14)(q23;q32) chromosomal translocation observed in human B… (More)
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2015
2015
DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways.
In adult tissues, stem and progenitor cells must balance proliferation and differentiation to maintain homeostasis. How this is… (More)
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2014
2014
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.
In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with the Immunochip array. Classical… (More)
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2013
2013
P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication.
In mammalian cells, proteins involved in mRNA silencing and degradation localize to discrete cytoplasmic foci called processing… (More)
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2013
2013
Modulation of Hepatitis C Virus RNA Accumulation and Translation by DDX6 and miR-122 Are Mediated by Separate Mechanisms
DDX6 and other P-body proteins are required for efficient replication of Hepatitis C Virus (HCV) by unknown mechanisms. DDX6 has… (More)
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2013
2013
t(11;14)(q23;q32) involving IGH and DDX6 in nodal marginal zone lymphoma.
Nodal marginal zone lymphoma (NMZL) is a primary nodal B-cell lymphoma that shares morphological and immunophenotypic… (More)
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2010
2010
P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes.
In mammalian somatic cells, several pathways that converge on deadenylation, decapping, and 5'-3' degradation are found in… (More)
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1999
1999
Expression of two dead box genes (DDX1 and DDX6) is independent of that of MYCN in human neuroblastoma cell lines.
To examine whether two DEAD box genes, DDX1 and DDX6, would have some roles in the progression of tumors, we investigated the… (More)
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