DDB2 gene

Known as: DDBB, DDB, p48 SUBUNIT, DNA DAMAGE-BINDING PROTEIN 2 
This gene plays a role in DNA repair.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent removal of ultraviolet (UV)-induced DNA… (More)
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Highly Cited
2009
Highly Cited
2009
The xeroderma pigmentosum complementation group E (XP-E) gene product damaged-DNA binding protein 2 (DDB2) plays important roles… (More)
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Highly Cited
2008
Highly Cited
2008
Ultraviolet (UV) light-induced pyrimidine photodimers are repaired by the nucleotide excision repair pathway. Photolesions have… (More)
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Highly Cited
2007
Highly Cited
2007
Damage DNA binding protein 2 (DDB2) has a high affinity for UV-damaged DNA and has been implicated in the initial steps of global… (More)
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Highly Cited
2006
Highly Cited
2006
Xeroderma pigmentosum (XP) complementation group E gene product, damaged DNA-binding protein 2 (DDB2), is a subunit of the DDB… (More)
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Highly Cited
2006
Highly Cited
2006
Xeroderma pigmentosum (XP) is a heritable human disorder characterized by defects in nucleotide excision repair (NER) and the… (More)
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Highly Cited
2005
Highly Cited
2005
The DDB protein complex, comprising the subunits DDB1 and DDB2, binds tightly to UV light-irradiated DNA. Mutations in DDB2 are… (More)
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Highly Cited
2003
Highly Cited
2003
Nucleotide excision repair (NER) is a major cellular defense against the carcinogenic effects of ultraviolet light from the sun… (More)
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Highly Cited
2002
Highly Cited
2002
The DDB2 gene, which is mutated in xeroderma pigmentosum group E, enhances global genomic repair of cyclobutane pyrimidine dimers… (More)
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Highly Cited
2001
Highly Cited
2001
The damaged-DNA binding protein DDB consists of two subunits, DDB1 (127 kDa) and DDB2 (48 kDa). Mutations in the DDB2 subunit… (More)
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