DCMP Deaminase

Known as: Deaminase, Deoxycytidylate, Deoxycytidylate Aminohydrolase, Monophosphate Deaminase, Deoxycytidine 
An enzyme that catalyzes the hydrolytic deamination of deoxycytidylic acid to deoxyuridylic acid and ammonia. It plays an important role in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1960-2017
051019602017

Papers overview

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2007
2007
The chlorovirus PBCV-1, like many large double-stranded DNA-containing viruses, contains several genes that encode putative… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Gemcitabine is a nucleoside analogue with activity against solid tumors. Gemcitabine metabolic inactivation is catalyzed… (More)
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2006
2006
We determined the sequence of the 152,372 bp genome of phiYS40, a lytic tailed bacteriophage of Thermus thermophilus. The genome… (More)
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Highly Cited
1992
Highly Cited
1992
2',2'-Difluorodeoxycytidine (dFdC, Gemcitabine) is a deoxycytidine analogue which, after phosphorylation to the 5'-di- and 5… (More)
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1987
1987
DNA precursor imbalances are known to be mutagenic in both eukaryotic and prokaryotic systems. Almost certainly, such mutagenesis… (More)
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1987
1987
A mutant V79 hamster fibroblast cell line lacking the enzyme dCMP deaminase was used to study the regulation of deoxynucleoside… (More)
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1986
1986
The dCMP deaminase gene (DCD1) of Saccharomyces cerevisiae has been isolated by screening a Sau3A clone bank for complementation… (More)
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1985
1985
Cytosine arabinoside (araC) has proven efficacy in acute myeloid leukemia (AML), but its place in the treatment of acute… (More)
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1981
1981
Recent studies of in vitro DNA synthesis have shown that fidelity of replication is influenced by the relative concentrations of… (More)
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1979
1979
Methotrexate (MTX) inhibition of the growth of mouse or human leukemia cells in culture was partially prevented by either… (More)
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