DCC gene

Known as: DELETED IN COLORECTAL CARCINOMA, DCC Genes, DCC 
Tumor suppressor genes located in the 18q21-qter region of human chromosome 18. The absence of these genes is associated with the formation of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
020406019512017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Extracellular signals regulate protein translation in many cell functions. A key advantage of control at the translational level… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
During nervous system development, spinal commissural axons project toward and across the ventral midline. They are guided in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Netrins promote axon outgrowth and turning through DCC/UNC-40 receptors. To characterize Netrin signaling, we generated a gain-of… (More)
  • figure 1
  • table 1
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The expression of DCC (deleted in colorectal cancer) is often markedly reduced in colorectal and other cancers. However, the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The development of colonic carcinoma is associated with the mutation of a specific set of genes. One of these, DCC (deleted in… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Embryonic retinal ganglion cell (RGC) axons must extend toward and grow through the optic disc to exit the eye into the optic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
UNC-6 netrin, a laminin-related protein secreted from neuroglia and neurons along the ventral midline, orients migrating cells… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
BACKGROUND Allelic loss of chromosome 18q predicts a poor outcome in patients with stage II colorectal cancer. Although the… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
DCC is a candidate tumor-suppressor gene encoding a protein with sequence similarity to cell adhesion molecules such as N-CAM. A… (More)
Is this relevant?