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D-serine biosynthetic process

Known as: D-serine anabolism, D-serine synthesis, D-serine biosynthesis 
The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D… 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Significance Phgdh is a crucial enzyme in the astrocytic synthesis of l-serine from glucose. Our study uncovers the role of glial… 
2018
2018
Significance d-serine regulates synaptic plasticity and behavior by binding to the NMDA receptors. Astrocyte–neuron cross-talk… 
2017
2017
It is long acknowledged that the N-methyl d-aspartate receptor co-agonist, d-serine, plays a crucial role in several N-methyl d… 
2017
2017
Central chemoreception is essential for adjusting breathing to physiological demands, and for maintaining CO2 and pH homeostasis… 
2017
2017
We provide evidence that NMDARs within murine spinal locomotor networks determine the frequency and amplitude of ongoing… 
2014
2014
Background: Serine racemase produces d-serine, which is required for optimal NMDA receptor activity. Results: FBXO22 interacts… 
Highly Cited
2009
Highly Cited
2009
Abnormal N-methyl-d-aspartate receptor (NMDAR) function has been implicated in the pathophysiology of schizophrenia. d-serine is… 
Review
2008
Review
2008
It has been recently established that in various brain regions d‐serine, the product of serine racemase, occupies the so‐called… 
Highly Cited
2001
Highly Cited
2001
Serine racemase is a brain-enriched enzyme that synthesizes d-serine, an endogenous modulator of the glycine site of N-methyl-d…