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D-serine biosynthetic process

Known as: D-serine anabolism, D-serine synthesis, D-serine biosynthesis 
The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Recombinant protein overexpressed in Escherichia coli is often less folded, leading to form the insoluble aggregates also called… Expand
2019
2019
Significance Phgdh is a crucial enzyme in the astrocytic synthesis of l-serine from glucose. Our study uncovers the role of glial… Expand
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2018
2018
Significance d-serine regulates synaptic plasticity and behavior by binding to the NMDA receptors. Astrocyte–neuron cross-talk… Expand
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2017
2017
It is long acknowledged that the N-methyl d-aspartate receptor co-agonist, d-serine, plays a crucial role in several N-methyl d… Expand
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2017
2017
Central chemoreception is essential for adjusting breathing to physiological demands, and for maintaining CO2 and pH homeostasis… Expand
2017
2017
We provide evidence that NMDARs within murine spinal locomotor networks determine the frequency and amplitude of ongoing… Expand
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2014
2014
Background: Serine racemase produces d-serine, which is required for optimal NMDA receptor activity. Results: FBXO22 interacts… Expand
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Review
2010
Review
2010
Schizophrenia is a severe mental disorder associated with a characteristic constellation of symptoms and neurocognitive deficits… Expand
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Highly Cited
2009
Highly Cited
2009
Abnormal N-methyl-d-aspartate receptor (NMDAR) function has been implicated in the pathophysiology of schizophrenia. d-serine is… Expand
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Highly Cited
2001
Highly Cited
2001
Serine racemase is a brain-enriched enzyme that synthesizes d-serine, an endogenous modulator of the glycine site of N-methyl-d… Expand
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