Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

D-serine biosynthetic process

Known as: D-serine anabolism, D-serine synthesis, D-serine biosynthesis 
The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Astrocytes express the 3-phosphoglycerate dehydrogenase (Phgdh) enzyme required for the synthesis of l-serine from glucose… Expand
Is this relevant?
2018
2018
d-serine is a physiologic coagonist of NMDA receptors, but little is known about the regulation of its synthesis and synaptic… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2017
2017
It is long acknowledged that the N-methyl d-aspartate receptor co-agonist, d-serine, plays a crucial role in several N-methyl d… Expand
  • figure 2
  • figure 3
  • figure 4
  • table 1
  • figure 5
Is this relevant?
2017
2017
Central chemoreception is essential for adjusting breathing to physiological demands, and for maintaining CO2 and pH homeostasis… Expand
Is this relevant?
2017
2017
Activation of N-methyl-d-aspartate receptors (NMDARs) requires the binding of a coagonist, either d-serine or glycine, in… Expand
  • figure 2
  • figure 3
  • figure 5
  • figure 6
  • figure 7
Is this relevant?
2014
2014
Background: Serine racemase produces d-serine, which is required for optimal NMDA receptor activity. Results: FBXO22 interacts… Expand
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Review
2010
Review
2010
Schizophrenia is a severe mental disorder associated with a characteristic constellation of symptoms and neurocognitive deficits… Expand
  • figure 1
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Abnormal N-methyl-d-aspartate receptor (NMDAR) function has been implicated in the pathophysiology of schizophrenia. d-serine is… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2008
Review
2008
It has been recently established that in various brain regions D-serine, the product of serine racemase, occupies the so-called… Expand
Is this relevant?
2001
2001
Serine racemase is a brain-enriched enzyme that synthesizes d-serine, an endogenous modulator of the glycine site of N-methyl-d… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?