Cytotoxic Granule Protein

Known as: CGP 
A protein that is stored in the secretory granules of cytotoxic leukocytes and plays a role in cell-mediated cytolysis.

Topic mentions per year

Topic mentions per year

1951-2018
05010015019512017

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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is… (More)
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Highly Cited
2000
Highly Cited
2000
STI571 (formerly known as CGP 57148B) is a protein-tyrosine kinase inhibitor that is currently in clinical trials for the… (More)
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Highly Cited
2000
Highly Cited
2000
STI 571 (formerly known as CGP 57148B) is a known inhibitor of the c-abl, bcr-abl, and platelet-derived growth-factor receptor… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND beta-Adrenergic receptor (beta-AR) stimulation increases apoptosis in adult rat cardiac (ventricular) myocytes (ARVMs… (More)
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Highly Cited
1997
Highly Cited
1997
CGP 57148 is a compound of the 2-phenylaminopyrimidine class that selectively inhibits the tyrosine kinase activity of the ABL… (More)
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Highly Cited
1996
Highly Cited
1996
Oncogenic activation of Abl proteins due to structural modifications can occur as a result of viral transduction or chromosomal… (More)
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Highly Cited
1995
Highly Cited
1995
Angiotensin II (ANG II) is known to be a potent growth promoting factor for vascular smooth muscle cells and fibroblasts but… (More)
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Highly Cited
1995
Highly Cited
1995
Repeated restraint stress of rats for 21 days causes atrophy of apical dendrites of hippocampal CA3c pyramidal neurons. This… (More)
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Highly Cited
1994
Highly Cited
1994
In the adult female rat, the densities of dendritic spines and synapses on hippocampal CA1 pyramidal cells are dependent upon the… (More)
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