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Cytokine-Induced Killer Cells

Known as: Cytokine-Induced Killer Cell, Killer Cells, Cytokine-Induced, Killer Cell, Cytokine-Induced 
A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3… 
National Institutes of Health

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MicrobiologicalNCIt Antineoplastic Agent TerminologyProcess of secretionaspects of radiation effects

Papers overview

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Review
2017
Review
2017
Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy
Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3+CD56+ natural killer T cells, which can be… 
Highly Cited
2013
Highly Cited
2013
Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor
Current therapeutic regimens for acute myeloid leukaemia (AML) are still associated with high rates of relapse. Immunotherapy… 
Review
2013
Review
2013
Cytokine-induced killer cells promote antitumor immunity
The number of immune cells, especially dendritic cells and cytotoxic tumor infiltrating lymphocytes (TIL), particularly Th1 cells… 
Highly Cited
2013
Highly Cited
2013
Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation".
Cytokine-induced killer (CIK) cells raised interest for use in cellular antitumor therapy due to their capability to recognize… 
Review
2011
Review
2011
Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors
Cytokine-induced killer (CIK) cells are a heterogeneous subset of ex-vivo expanded T lymphocytes which present a mixed T-NK… 
Highly Cited
2009
Highly Cited
2009
Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: a pilot clinical trial
Background and Objectives: CIK cells are a novel population of efficient immune effector cells with high antitumour activity… 
Highly Cited
2008
Highly Cited
2008
In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity.
Cytokine-induced killer (CIK) cells are ex vivo-expanded T lymphocytes expressing both natural killer (NK)- and T-cell markers… 
Review
1997
Review
1997
Activated T cells and cytokine-induced CD3+CD56+ killer cells
Abstract Over the past two decades, attempts have been made to develop immunotherapy for patients with cancer. A significant… 
Highly Cited
1994
Highly Cited
1994
A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency.
Recently, we have reported a novel protocol for the generation of highly efficient cytotoxic effector cells by culturing PBLs in… 
Highly Cited
1993
Highly Cited
1993
Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells.
Cytokine-induced killer (CIK) cells are highly efficient cytotoxic effector cells capable of lysing tumor cell targets. Cultures… 
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