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Cytochrome P450 2A5

Mouse cytochrome P450 2a5 protein (494 aa, 57 kD) is encoded by the mouse Cyp2a5 gene. This enzyme is an unspecific, membrane-bound, monooxygenase… Expand
National Institutes of Health

Papers overview

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2017
2017
BackgroundCytochrome P450 2A5 (Cyp2a5), a mouse enzyme orthologous of human CYP2A6, catalyzes a number of toxicologically… Expand
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2013
2013
Bilirubin (BR) has recently been identified as the first endogenous substrate for cytochrome P450 2A5 (CYP2A5) and it has been… Expand
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2013
2013
Mouse cytochrome P450 2A5 (CYP2A5) is upregulated in various liver diseases and a putative common feature for all of these… Expand
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2011
2011
We have previously shown that bilirubin (BR), a breakdown product of haem, is a strong inhibitor and a high affinity substrate of… Expand
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2010
2010
Mouse cytochrome P450 2A5 (CYP2A5) is upregulated in various pathophysiological liver diseases and induced by structurally… Expand
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2008
2008
Murine hepatic cytochrome P450 2A5 (CYP2A5), unlike most CYP enzymes, is upregulated during hepatitis and hepatotoxic conditions… Expand
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2008
2008
Cytochrome P450 2a5 (Cyp2a5) expression is induced during liver damage caused by hepatotoxins such as pyrazole, however, the… Expand
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2005
2005
Oxidative metabolism of bilirubin (BR) -- a breakdown product of haem with cytoprotective and toxic properties -- is an important… Expand
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2004
2004
Murine hepatic cytochrome P450 2A5 (CYP2A5) is uniquely induced by a variety of agents that cause liver injury and inflammation… Expand
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2003
2003
Murine hepatic cytochrome P450 2a5 (Cyp2a5) is induced during hepatotoxicity and hepatitis, however, the specific regulatory… Expand
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