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Cytochrome P450 2A5

Mouse cytochrome P450 2a5 protein (494 aa, 57 kD) is encoded by the mouse Cyp2a5 gene. This enzyme is an unspecific, membrane-bound, monooxygenase… 
National Institutes of Health

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Cytochrome P450Mus

Papers overview

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2017
2017
Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis.
2017
2017
Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver
BackgroundCytochrome P450 2A5 (Cyp2a5), a mouse enzyme orthologous of human CYP2A6, catalyzes a number of toxicologically… 
2015
2015
Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.
2011
2011
Inducible bilirubin oxidase: a novel function for the mouse cytochrome P450 2A5.
Highly Cited
2010
Highly Cited
2010
Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver.
Mouse cytochrome P450 2A5 (CYP2A5) is upregulated in various pathophysiological liver diseases and induced by structurally… 
2008
2008
Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction.
Highly Cited
2005
Highly Cited
2005
Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5.
Highly Cited
2004
Highly Cited
2004
Endoplasmic Reticulum Stress Due to Altered Cellular Redox Status Positively Regulates Murine Hepatic CYP2A5 Expression
Murine hepatic cytochrome P450 2A5 (CYP2A5) is uniquely induced by a variety of agents that cause liver injury and inflammation… 
2003
2003
Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.
2003
2003
Cell-specific Expression of CYP2A5 in the Mouse Respiratory Tract: Effects of Olfactory Toxicants
We performed a detailed analysis of mouse cytochrome P450 2A5 (CYP2A5) expression by in situ hybridization (ISH) and… 
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