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Cytochrome P450 26A1, human
Known as:
Cytochrome P450RAI
, Retinoic Acid-Metabolizing Cytochrome
, EC 1.14.-.-
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Cytochrome P450 26A1 (497 aa, ~56 kDa) is encoded by the human CYP26A1 gene. This protein is involved in the hydroxylation of retinoic acid.
National Institutes of Health
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Related topics
Related topics
13 relations
CYP26A1 gene
Cytochrome P450 26B1, human
Enzyme Gene
Hemeproteins
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Broader (1)
retinoic acid 4-hydroxylase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.
M. Osanai
,
A. Takasawa
,
Kumi Takasawa
,
M. Murata
,
N. Sawada
Oncology Letters
2018
Corpus ID: 21674757
Elevated expression of the retinoic acid-metabolizing enzyme cytochrome P450 26A1 (CYP26A1) has been demonstrated to have an…
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2016
2016
Dietary vitamin A supplementation improved reproductive performance by regulating ovarian expression of hormone receptors, caspase-3 and Fas in broiler breeders.
Fang Chen
,
Zong-yong Jiang
,
+4 authors
Q. Fan
Poultry Science
2016
Corpus ID: 10011935
The effects of dietary vitamin A (VA) supplementation on reproductive performance, VA deposition, and potential mechanisms of…
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2016
2016
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy
Chao-yang Meng
,
Zhong-Yin Li
,
+5 authors
Jing-Pian Peng
Journal of Cellular and Molecular Medicine
2016
Corpus ID: 6217873
Cytochrome P450 26A1 (CYP26A1) has a spatiotemporal expression pattern in the uterus, with a significant increase in mRNA and…
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Highly Cited
2015
Highly Cited
2015
Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor.
Gregory M Isales
,
Rachel A. Hipszer
,
Tara D. Raftery
,
Albert Chen
,
H. Stapleton
,
D. Volz
Aquatic Toxicology
2015
Corpus ID: 43391866
2013
2013
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation
Hai-yan Liu
,
H. Chao
,
+4 authors
Jing-Pian Peng
Journal of Cellular and Molecular Medicine
2013
Corpus ID: 14561813
Cytochrome P450 26A1 (cyp26a1) is expressed in the mouse uterus during peri‐implantation. The repression of this protein is…
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2012
2012
Retinoic acid synthesis and metabolism are concurrent in the mouse uterus during peri-implantation
Jing-jing Ma
,
Bing-chen Han
,
Ying Yang
,
Jing-Pian Peng
Cell and Tissue Research
2012
Corpus ID: 253970364
Vitamin A (retinol) and its active metabolite, retinoic acid (RA), serve dual roles in the female reproductive tract. Cytochrome…
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2011
2011
Altered expression of both β-carotene 15,15' monooxygenase and lecithin:retinol acyltransferase in obese Zucker rats.
K. Takitani
,
H. Miyazaki
,
+4 authors
H. Tamai
Journal of Nutritional Science and Vitaminology
2011
Corpus ID: 3541562
Retinol and its active derivative retinoic acid have an important role in development, reproduction, immunity, and cell…
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Highly Cited
2008
Highly Cited
2008
Ligand Activation of Peroxisome Proliferator-Activated Receptor-β/δ Inhibits Cell Proliferation in Human HaCaT Keratinocytes
Michael G. Borland
,
J. E. Foreman
,
+6 authors
J. Peters
Molecular Pharmacology
2008
Corpus ID: 19728276
Although there is strong evidence that ligand activation of peroxisome proliferator-activated receptor (PPAR)-β/δ induces…
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2004
2004
Identification of the Fenretinide Metabolite 4-Oxo-Fenretinide Present in Human Plasma and Formed in Human Ovarian Carcinoma Cells through Induction of Cytochrome P450 26A1
M. G. Villani
,
V. Appierto
,
+4 authors
F. Formelli
Clinical Cancer Research
2004
Corpus ID: 1590254
Purpose: The synthetic retinoid fenretinide (4-HPR) exhibits preventive and therapeutic activity against ovarian tumors. An…
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Highly Cited
1997
Highly Cited
1997
cDNA Cloning of Human Retinoic Acid-metabolizing Enzyme (hP450RAI) Identifies a Novel Family of Cytochromes P450 (CYP26)*
J. White
,
B. Beckett-Jones
,
+4 authors
M. Petkovich
Journal of Biological Chemistry
1997
Corpus ID: 26838003
Retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA play important roles in regulating gene…
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