FAQ

Cytochrome P450 26A1, human

Known as: Cytochrome P450RAI, Retinoic Acid-Metabolizing Cytochrome, EC 1.14.-.- 
Cytochrome P450 26A1 (497 aa, ~56 kDa) is encoded by the human CYP26A1 gene. This protein is involved in the hydroxylation of retinoic acid.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
0119972016

Related topics

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12 relations
CYP26A1 geneCytochrome P450 Family GeneEnzyme GeneHemeproteins
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Broader (1)

retinoic acid 4-hydroxylase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Cytochrome P450 26A1, human
Oxidation-Reduction
Metabolic Detoxication, Drug
Metabolism
Hemeproteins
CYP26A1 gene

Papers overview

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2017
2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy
Cytochrome P450 26A1 (CYP26A1) has a spatiotemporal expression pattern in the uterus, with a significant increase in mRNA and… (More)
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2016
2016
Effect of NADPH-cytochrome P450 reductase on all-trans-retinoic acid efficacy and cytochrome P450 26A1 expression in human myeloid leukaemia HL-60 cells.
OBJECTIVES All-trans-retinoic acid (ATRA), a naturally occurring metabolite of vitamin A, has been shown to have great potential… (More)
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2014
2014
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation
Cytochrome P450 26A1 (cyp26a1) is expressed in the mouse uterus during peri-implantation. The repression of this protein is… (More)
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2012
2012
Retinoic acid synthesis and metabolism are concurrent in the mouse uterus during peri-implantation
Vitamin A (retinol) and its active metabolite, retinoic acid (RA), serve dual roles in the female reproductive tract. Cytochrome… (More)
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2011
2011
Altered expression of both β-carotene 15,15' monooxygenase and lecithin:retinol acyltransferase in obese Zucker rats.
Retinol and its active derivative retinoic acid have an important role in development, reproduction, immunity, and cell… (More)
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2010
2010
Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (cyp26a1) is essential for implantation: functional study of its role in early pregnancy.
Vitamin A (VA) is required for normal fetal development and successful pregnancy. Excessive VA intake during pregnancy may lead… (More)
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2008
2008
Homology Models and Molecular Modeling of Human Retinoic Acid Metabolizing Enzymes Cytochrome P450 26A1 (CYP26A1) and P450 26B1 (CYP26B1).
Homology models of cytochrome P450 26A1 and cytochrome P450 26B1 were constructed using the crystal structures of human, CYP2C8… (More)
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Highly Cited
1997
Highly Cited
1997
cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.
Retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA play important roles in regulating gene… (More)
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