Skip to search formSkip to main contentSkip to account menu

Cytochrome P-450 CYP3A5

Known as: P-450 CYP3A5, Cytochrome, Cytochrome P450 3A5, CYP3A5 
A specific subtype of CYP3A.
National Institutes of Health

Related topics

Related topics

2 relations
CYP3A5 gene

Broader (1)

cytochrome P450 3A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Effect of CYP3A5*3 genotype on the pharmacokinetics and antiplatelet effect of clopidogrel in healthy subjects
ObjectiveClopidogrel is activated by cytochrome P450 3A (CYP3A) to generate an active metabolite that inhibits adenosine… 
2008
2008
Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipients
Highly Cited
2006
Highly Cited
2006
Common sequence variations in the P2Y12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy
The efficacy of the platelet P2Y12 receptor antagonist clopidogrel, which undergoes cytochrome-mediated metabolism to its active… 
2006
2006
Enzymatic characteristics of CYP3A5 and CYP3A4: A comparison of in vitro kinetic and drug–drug interaction patterns
CYP3A4 and CYP3A5 exhibit significant overlap in substrate specificity, but can differ in catalytic activity and regioselectivity… 
Highly Cited
2005
Highly Cited
2005
Differences in CYP3A5*3 Genotype Distribution and Combinations With Other Polymorphisms Between Spaniards and Other Caucasian Populations
The goal of this study was to detect genotypic differences between Spaniards and other related populations regarding CYP3A4*1B… 
Highly Cited
2004
Highly Cited
2004
CYP3A5 Polymorphism and the Ethnic Differences in Cyclosporine Pharmacokinetics in Healthy Subjects 1
To determine the relationship between CYP3A5 polymorphism and cyclosporine pharmacokinetic parameters among healthy volunteers… 
2004
2004
CYP3A5 Genotype has a Dose‐dependent Effect on ABT‐773 Plasma Levels
Review
2003
Review
2003
A significant drug-metabolizing role for CYP3A5?
Recent research on CYP3A5 in vitro and in humans has provided discordant information on whether CYP3A5 plays a significant role… 
2003
2003
Cytochrome P450 3A pharmacogenetics: the road that needs traveled
‘The woods are lovely, dark and deep But I have promises to keep And miles to go before I sleep And miles to go before I sleep… 
2002
2002
COMPARATIVE METABOLIC CAPABILITIES OF CYP 3 A 4 , CYP 3 A 5 , AND CYP 3 A 7
The human cytochromes P450 (P450) CYP3A contribute to the biotransformation of 50% of oxidatively metabolized drugs. The… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)