Cystic Fibrosis Transmembrane Conductance Regulator

Known as: CFTR, CFTR Protein, cystic fibrosis transmembrane conductance regulator (CFTR) protein 
A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
RATIONALE Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator recently approved for patients… (More)
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Highly Cited
2010
Highly Cited
2010
RATIONALE Nonsense (premature stop codon) mutations in mRNA for the cystic fibrosis transmembrane conductance regulator (CFTR… (More)
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Highly Cited
2004
Highly Cited
2004
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-binding cassette (ABC) transporter that functions as a… (More)
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Highly Cited
2002
Highly Cited
2002
Estimates of the level of transcripts from the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene required to… (More)
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Highly Cited
1996
Highly Cited
1996
Mice that have been made deficient for the cystic fibrosis transmembrane conductance regulator (Cftr) usually die of intestinal… (More)
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Highly Cited
1994
Highly Cited
1994
The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl- channel regulated by protein kinase A. The… (More)
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Highly Cited
1992
Highly Cited
1992
Direct transfer of the normal cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene to airway epithelium was… (More)
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Highly Cited
1992
Highly Cited
1992
Cystic fibrosis is caused by mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR). To… (More)
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Highly Cited
1991
Highly Cited
1991
Cystic fibrosis (CF) is characterized by an abnormality in cAMP-regulated chloride transport that results from a primary defect… (More)
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Highly Cited
1990
Highly Cited
1990
The cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in cultured cystic fibrosis airway epithelial cells… (More)
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