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Cystic Fibrosis Transmembrane Conductance Regulator

Known as: CFTR, CFTR Protein, cystic fibrosis transmembrane conductance regulator (CFTR) protein 
A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The cystic fibrosis transmembrane conductance regulator (CFTR) belongs to the ATP binding cassette (ABC) transporter superfamily… Expand
Review
2018
Review
2018
Cystic Fibrosis (CF) is a genetic disorder that arises due to mutations in the Cystic Fibrosis Transmembrane Conductance… Expand
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Highly Cited
2014
Highly Cited
2014
RATIONALE Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator recently approved for patients… Expand
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Highly Cited
2004
Highly Cited
2004
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP‐binding cassette (ABC) transporter that functions as a… Expand
Highly Cited
1996
Highly Cited
1996
Mice that have been made deficient for the cystic fibrosis transmembrane conductance regulator (Cftr) usually die of intestinal… Expand
Highly Cited
1994
Highly Cited
1994
The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl- channel regulated by protein kinase A. The… Expand
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Highly Cited
1992
Highly Cited
1992
Circumstantial evidence has accumulated suggesting that CFTR is a regulated low-conductance Cl- channel. To test this postulate… Expand
Highly Cited
1992
Highly Cited
1992
Direct transfer of the normal cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene to airway epithelium was… Expand
Highly Cited
1991
Highly Cited
1991
Cystic fibrosis (CF) is characterized by an abnormality in cAMP-regulated chloride transport that results from a primary defect… Expand
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Highly Cited
1990
Highly Cited
1990
The cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in cultured cystic fibrosis airway epithelial cells… Expand