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Cyclobenzaprine hydrochloride

Known as: 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, Hydrochloride, cyclobenzaprine hcl, 10,11delta-Amitriptyline Hydrochloride 
A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Abstract The purpose of present investigation was to formulate and characterize the cyclobenzaprine HCl (CBZ)-loaded thiolated… Expand
2011
2011
Two cyclobenzaprine hydrochloride (CZ) microsized graphite selective sensors were investigated with dibutylsebacate as a… Expand
2004
2004
OBJECTIVE To determine the weight variation and calculated dosing variability of tablet fragments upon splitting unscored… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Cyclobenzaprine hydrochloride is a muscle relaxant that is effective in improving muscle spasm, reducing local pain… Expand
2002
2002
ABSTRACT Oral osmotic delivery systems containing polyethylene oxide (PEO, a water-swellable polymer) were designed and the… Expand
2002
2002
ABSTRACT Osmotically rupturable systems were developed and the release of cyclobenzaprine hydrochloride (model drug) from the… Expand
Highly Cited
1989
Highly Cited
1989
A double-blind, 18-center, balanced trial of diflunisal vs. cyclobenzaprine HCl vs. these two drugs combined vs. placebo produced… Expand
Highly Cited
1978
Highly Cited
1978
: A new drug, Cyclobenzaprine hydrochloride (Flexeril), was compared with diazepam (Valium) and placebo in double-blind trials… Expand
1978
1978
The effectiveness of cyclobenzaprine hydrochloride, a new tricyclic skeletal muscle relaxant, was shown in patients with long… Expand
1978
1978
  • J. Basmajian
  • Archives of physical medicine and rehabilitation
  • 1978
  • Corpus ID: 37143231
A new drug, Cyclobenzaprine hydrochloride (Flexeril), was compared with diazepam (Valium) and placebo in double-blind trials for… Expand