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Cyclin D

Known as: Cyclins, Type D, D Cyclins, Type, Type D Cyclin 
A cyclin subtype that is specific for CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. Unlike most cyclins, cyclin D expression is not… 
National Institutes of Health

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Cell Cycle ProgressionCyclinsIn BloodProcess of secretion

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Cyclin D1

Papers overview

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Review
2007
Review
2007
PTEN, a general negative regulator of cyclin D expression
The tumor-suppressor phosphatase with tensin homology (PTEN) is frequently mutated in many malignancies and is one of the most… 
2005
2005
Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumor.
Highly Cited
2001
Highly Cited
2001
Role of Cyclin D3 in the Biology of Herpes Simplex Virus 1 ICP0
ABSTRACT Earlier reports from this laboratory have shown that the promiscuous transactivator infected-cell protein 0 (ICP0) binds… 
2000
2000
Differential expression of cell-cell adhesion proteins and cyclin D in MEK1-transdifferentiated MDCK cells.
Overexpression of a constitutively active mutant of the mitogen-activated protein kinase kinase MEK1 (caMEK1) in epithelial Madin… 
1999
1999
Overexpression of Cyclin D 1 Messenger RNA Predicts for Poor Prognosis in Estrogen Receptor-positive Breast Cancer 1
Cyclin D1 is a key cell cycle regulatory protein with demonstrated oncogenic activity in a variety of malignancies. Cyclin D1… 
1998
1998
Regulation of cyclin D-dependent kinase activity in rat liver regeneration.
The regulation of cyclin D-dependent kinase activity in tissue regeneration in vivo has not been fully described. In young adult… 
Highly Cited
1996
Highly Cited
1996
Defective Folding of Mutant p16INK4 Proteins Encoded by Tumor-derived Alleles*
p16INK4 is a specific cyclin D-dependent kinase inhibitor and a multiple tumor suppressor. Inactivation of p16 is frequent in… 
Highly Cited
1995
Highly Cited
1995
Cyclin D and retinoblastoma gene product expression in actinic keratosis and cutaneous squamous cell carcinoma in relation to p53 expression
Masato Ueda, Abnormality of the molecules regulating the cell cycle has been shown to lead cells to transformation. Recently… 
1995
1995
Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo[a]pyrene.
Squamous cell carcinomas (SCCs) of the mouse skin, as well as several types of preinvasive carcinoma precursor lesions, were… 
1994
1994
Staurosporine blocks cell progression through G1 between the cyclin D and cyclin E restriction points.
The protein kinase inhibitor staurosporine (SSP) stops progression of normal nontransformed cells in the G1 phase of the cell… 
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